Mediobasal hypothalamic overexpression of DEPTOR protects against high-fat diet-induced obesity

Mediobasal hypothalamic overexpression of DEPTOR protects against high-fat diet-induced obesity

Background/Objective: The mechanistic target of rapamycin (mTOR) is a serine–threonine kinase that functions into distinct protein complexes (mTORC1 and mTORC2) that regulate energy homeostasis. DEP-domain containing mTOR-interacting protein (DEPTOR) is part of these complexes and is known to dampen...

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Bibliographic Details
Main Authors: Caron, Alexandre, Labbé, Sébastien M., Lanfray, Damien, Blanchard, Pierre-Gilles, Villot, Romain, Roy, Christian, Richard, Denis, Laplante, Mathieu, Sabatini, David
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Elsevier 2016
Online Access:http://hdl.handle.net/1721.1/106150
https://orcid.org/0000-0002-1446-7256

Internet

http://hdl.handle.net/1721.1/106150
https://orcid.org/0000-0002-1446-7256

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