Mediobasal hypothalamic overexpression of DEPTOR protects against high-fat diet-induced obesity
Background/Objective: The mechanistic target of rapamycin (mTOR) is a serine–threonine kinase that functions into distinct protein complexes (mTORC1 and mTORC2) that regulate energy homeostasis. DEP-domain containing mTOR-interacting protein (DEPTOR) is part of these complexes and is known to dampen...
Main Authors: | Caron, Alexandre, Labbé, Sébastien M., Lanfray, Damien, Blanchard, Pierre-Gilles, Villot, Romain, Roy, Christian, Richard, Denis, Laplante, Mathieu, Sabatini, David |
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Other Authors: | Massachusetts Institute of Technology. Department of Biology |
Format: | Article |
Language: | en_US |
Published: |
Elsevier
2016
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Online Access: | http://hdl.handle.net/1721.1/106150 https://orcid.org/0000-0002-1446-7256 |
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