SCARB2/LIMP-2 Regulates IFN Production of Plasmacytoid Dendritic Cells by Mediating Endosomal Translocation of TLR9 and Nuclear Translocation of IRF7

SCARB2/LIMP-2 Regulates IFN Production of Plasmacytoid Dendritic Cells by Mediating Endosomal Translocation of TLR9 and Nuclear Translocation of IRF7

Scavenger receptor class B, member 2 (SCARB2) is essential for endosome biogenesis and reorganization and serves as a receptor for both β-glucocerebrosidase and enterovirus 71. However, little is known about its function in innate immune cells. In this study, we show that, among human peripheral blo...

Full description

Bibliographic Details
Main Authors: Guo, H., Zhang, J., Zhang, X., Wang, Y., Yu, H., Yin, X., Li, J., Du, P., Plumas, J., Chaperot, L., Su, L., Liu, Y., Zhang, L., Chen, Jianzhu
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: American Association of Immunologists 2017
Online Access:http://hdl.handle.net/1721.1/106316
https://orcid.org/0000-0002-5687-6154

Internet

http://hdl.handle.net/1721.1/106316
https://orcid.org/0000-0002-5687-6154

Similar Items