Usp12 stabilizes the T-cell receptor complex at the cell surface during signaling

Posttranslational modifications are central to the spatial and temporal regulation of protein function. Among others, phosphorylation and ubiquitylation are known to regulate proximal T-cell receptor (TCR) signaling. Here we used a systematic and unbiased approach to uncover deubiquitylating enzymes...

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מידע ביבליוגרפי
Main Authors: Jahan, Akhee S., Lestra, Maxime, Swee, Lee Kim, Fan, Ying, Lamers, Mart M., Tafesse, Fikadu G., Theile, Christopher S., Spooner, Eric, Bruzzone, Roberto, Sanyal, Sumana, Ploegh, Hidde
מחברים אחרים: Massachusetts Institute of Technology. Department of Biology
פורמט: Article
שפה:en_US
יצא לאור: National Academy of Sciences (U.S.) 2017
גישה מקוונת:http://hdl.handle.net/1721.1/106472
https://orcid.org/0000-0002-1090-6071