Recurrent mTORC1-activating RRAGC mutations in follicular lymphoma

Follicular lymphoma is an incurable B cell malignancy characterized by the t(14;18) translocation and mutations affecting the epigenome. Although frequent gene mutations in key signaling pathways, including JAK-STAT, NOTCH and NF-κB, have also been defined, the spectrum of these mutations typically...

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Bibliographic Details
Main Authors: Sabatini, David, Wolfson, Rachel Laura, Efeyan, Alejo
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Nature Publishing Group 2017
Online Access:http://hdl.handle.net/1721.1/106517
https://orcid.org/0000-0002-1446-7256
https://orcid.org/0000-0002-9535-7664

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