SHMT2 drives glioma cell survival in ischaemia but imposes a dependence on glycine clearance
Cancer cells adapt their metabolic processes to support rapid proliferation, but less is known about how cancer cells alter metabolism to promote cell survival in a poorly vascularized tumour microenvironment1, 2, 3. Here we identify a key role for serine and glycine metabolism in the survival of br...
| Main Authors: | , , , , , , , , , , , , , , , , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | en_US |
| Published: |
Nature Publishing Group
2017
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| Online Access: | http://hdl.handle.net/1721.1/106619 https://orcid.org/0000-0002-2401-0030 https://orcid.org/0000-0003-3688-2378 https://orcid.org/0000-0002-7043-5013 https://orcid.org/0000-0003-0130-3428 https://orcid.org/0000-0002-6702-4192 https://orcid.org/0000-0002-1446-7256 |