Articular cartilage of the knee 3 years after ACL reconstruction
Background and purpose: T1ρ or T2 relaxation imaging has been increasingly used to evaluate the cartilage of the knee. We investigated the cartilage of ACL-reconstructed knees 3 years after surgery using T2 relaxation times. Patients and methods: 10 patients with a clinically successful unilateral...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | en_US |
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Informa UK (Informa Healthcare)
2017
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| Online Access: | http://hdl.handle.net/1721.1/106622 https://orcid.org/0000-0002-4942-3456 |
| _version_ | 1826198318204583936 |
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| author | Bae, Ji-Hoon Hosseini, Ali Torriani, Martin Gill, Thomas J Li, Guoan Wang, Yang Grodzinsky, Alan J |
| author2 | Massachusetts Institute of Technology. Department of Biological Engineering |
| author_facet | Massachusetts Institute of Technology. Department of Biological Engineering Bae, Ji-Hoon Hosseini, Ali Torriani, Martin Gill, Thomas J Li, Guoan Wang, Yang Grodzinsky, Alan J |
| author_sort | Bae, Ji-Hoon |
| collection | MIT |
| description | Background and purpose: T1ρ or T2 relaxation imaging has been increasingly used to evaluate the cartilage of the knee. We investigated the cartilage of ACL-reconstructed knees 3 years after surgery using T2 relaxation times.
Patients and methods: 10 patients with a clinically successful unilateral ACL reconstruction were examined 3 years after surgery. Multiple-TE fast-spin echo sagittal images of both knees were acquired using a 3T MRI scanner for T2 mapping of the tibiofemoral cartilage. T2 values of the superficial and deep zones of the tibiofemoral cartilage were analyzed in sub-compartmental areas and compared between the ACL-reconstructed and uninjured contralateral knees.
Results: Higher T2 values were observed in 1 or more sub-compartmental areas of each ACL-reconstructed knee compared to the uninjured contralateral side. Most of the T2 increases were observed at the superficial zones of the cartilage, especially at the medial compartment. At the medial compartment of the ACL-reconstructed knee, the T2 values of the femoral and tibial cartilage were increased by 3–81% compared to the uninjured contralateral side, at the superficial zones of the weight-bearing areas. T2 values in the superficial zone of the central medial femoral condyle differed between the 2 groups (p = 0.002).
Interpretation: The articular cartilage of ACL-reconstructed knees, although clinically satisfactory, had higher T2 values in the superficial zone of the central medial femoral condyle than in the uninjured contralateral side 3 years after surgery. Further studies are warranted to determine whether these patients would undergo cartilage degeneration over time. |
| first_indexed | 2024-09-23T11:02:59Z |
| format | Article |
| id | mit-1721.1/106622 |
| institution | Massachusetts Institute of Technology |
| language | en_US |
| last_indexed | 2024-09-23T11:02:59Z |
| publishDate | 2017 |
| publisher | Informa UK (Informa Healthcare) |
| record_format | dspace |
| spelling | mit-1721.1/1066222022-09-27T16:45:23Z Articular cartilage of the knee 3 years after ACL reconstruction Bae, Ji-Hoon Hosseini, Ali Torriani, Martin Gill, Thomas J Li, Guoan Wang, Yang Grodzinsky, Alan J Massachusetts Institute of Technology. Department of Biological Engineering Wang, Yang Grodzinsky, Alan J Background and purpose: T1ρ or T2 relaxation imaging has been increasingly used to evaluate the cartilage of the knee. We investigated the cartilage of ACL-reconstructed knees 3 years after surgery using T2 relaxation times. Patients and methods: 10 patients with a clinically successful unilateral ACL reconstruction were examined 3 years after surgery. Multiple-TE fast-spin echo sagittal images of both knees were acquired using a 3T MRI scanner for T2 mapping of the tibiofemoral cartilage. T2 values of the superficial and deep zones of the tibiofemoral cartilage were analyzed in sub-compartmental areas and compared between the ACL-reconstructed and uninjured contralateral knees. Results: Higher T2 values were observed in 1 or more sub-compartmental areas of each ACL-reconstructed knee compared to the uninjured contralateral side. Most of the T2 increases were observed at the superficial zones of the cartilage, especially at the medial compartment. At the medial compartment of the ACL-reconstructed knee, the T2 values of the femoral and tibial cartilage were increased by 3–81% compared to the uninjured contralateral side, at the superficial zones of the weight-bearing areas. T2 values in the superficial zone of the central medial femoral condyle differed between the 2 groups (p = 0.002). Interpretation: The articular cartilage of ACL-reconstructed knees, although clinically satisfactory, had higher T2 values in the superficial zone of the central medial femoral condyle than in the uninjured contralateral side 3 years after surgery. Further studies are warranted to determine whether these patients would undergo cartilage degeneration over time. National Institute of Arthritis and Musculoskeletal and Skin Diseases (U.S.) (Grants R01 AR055612 and AR060331) 2017-01-25T20:12:58Z 2017-01-25T20:12:58Z 2015-09 2014-12 Article http://purl.org/eprint/type/JournalArticle 1745-3674 1745-3682 http://hdl.handle.net/1721.1/106622 Bae, Ji-Hoon et al. “Articular Cartilage of the Knee 3 Years after ACL Reconstruction: A Quantitative T2 Relaxometry Analysis of 10 Knees.” Acta Orthopaedica 86.5 (2015): 605–610. https://orcid.org/0000-0002-4942-3456 en_US http://dx.doi.org/10.3109/17453674.2015.1039426 Acta Orthopaedica Creative Commons Attribution-NonCommercial 4.0 International http://creativecommons.org/licenses/by-nc/4.0/ application/pdf Informa UK (Informa Healthcare) Informa Healthcare |
| spellingShingle | Bae, Ji-Hoon Hosseini, Ali Torriani, Martin Gill, Thomas J Li, Guoan Wang, Yang Grodzinsky, Alan J Articular cartilage of the knee 3 years after ACL reconstruction |
| title | Articular cartilage of the knee 3 years after ACL reconstruction |
| title_full | Articular cartilage of the knee 3 years after ACL reconstruction |
| title_fullStr | Articular cartilage of the knee 3 years after ACL reconstruction |
| title_full_unstemmed | Articular cartilage of the knee 3 years after ACL reconstruction |
| title_short | Articular cartilage of the knee 3 years after ACL reconstruction |
| title_sort | articular cartilage of the knee 3 years after acl reconstruction |
| url | http://hdl.handle.net/1721.1/106622 https://orcid.org/0000-0002-4942-3456 |
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