Designer nanoscale DNA assemblies programmed from the top down

Scaffolded DNA origami is a versatile means of synthesizing complex molecular architectures. However, the approach is limited by the need to forward-design specific Watson-Crick basepairing manually for any given target structure. Here, we report a general, top-down strategy to design nearly arbitr...

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Bibliographic Details
Main Authors: Zhang, K., Zhang, F., Yan, H., Chiu, W., Veneziano, Remi, Ratanalert, Sakul, Bathe, Mark
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: American Association for the Advancement of Science (AAAS) 2017
Online Access:http://hdl.handle.net/1721.1/106652
https://orcid.org/0000-0002-2726-3770
https://orcid.org/0000-0002-1766-807X
https://orcid.org/0000-0002-6199-6855

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