Th17 cytokines differentiate obesity from obesity-associated type 2 diabetes and promote TNFα production

Th17 cytokines differentiate obesity from obesity-associated type 2 diabetes and promote TNFα production

Objective: T cell inflammation plays pivotal roles in obesity-associated type 2 diabetes (T2DM). The identification of dominant sources of T cell inflammation in humans remains a significant gap in understanding disease pathogenesis. It was hypothesized that cytokine profiles from circulating T cell...

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Bibliographic Details
Main Authors: Ip, Blanche, Belkina, Anna C., DeFuria, Jason, Jagannathan-Bogdan, Madhumita, Zhu, Min, Kuchibhatla, Ramya, McDonnell, Marie E., Xiao, Qiang, Kepler, Thomas B., Apovian, Caroline M., Nikolajczyk, Barbara S., Cilfone, Nicholas A., Lauffenburger, Douglas A
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: Nature Publishing Group 2017
Online Access:http://hdl.handle.net/1721.1/106829

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