Discovery of bisamide-heterocycles as inhibitors of scavenger receptor BI (SR-BI)-mediated lipid uptake

Discovery of bisamide-heterocycles as inhibitors of scavenger receptor BI (SR-BI)-mediated lipid uptake

A new series of potent inhibitors of cellular lipid uptake from HDL particles mediated by scavenger receptor, class B, type I (SR-BI) was identified. The series was identified via a high-throughput screen of the National Institutes of Health Molecular Libraries Small Molecule Repository (NIH MLSMR)...

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Bibliographic Details
Main Authors:	Dockendorff, Chris, Faloon, Patrick W., Germain, Andrew, Youngsaye, Willmen, Nag, Partha P., Bennion, Melissa, Dandapani, Sivaraman, Perez, José R., Munoz, Benito, Palmer, Michelle A., Schreiber, Stuart L., Yu, Miao, Penman, Marsha L, Nieland, Thomas J, Krieger, Monty
Other Authors:	Massachusetts Institute of Technology. Department of Biology
Format:	Article
Language:	en_US
Published:	Elsevier 2017
Online Access:	http://hdl.handle.net/1721.1/106850 https://orcid.org/0000-0003-2673-1672 https://orcid.org/0000-0003-4541-5181

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