Modular combinatorial binding among human trans-acting factors reveals direct and indirect factor binding

Background The combinatorial binding of trans-acting factors (TFs) to the DNA is critical to the spatial and temporal specificity of gene regulation. For certain regulatory regions, more than one regulatory module (set of TFs that bind together) are combined to achieve context-specific gene regulat...

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Bibliographic Details
Main Authors: Guo, Yuchun, Gifford, David K
Other Authors: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory
Format: Article
Language:English
Published: BioMed Central 2017
Online Access:http://hdl.handle.net/1721.1/106853
https://orcid.org/0000-0003-2357-1546
https://orcid.org/0000-0003-1709-4034

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