Network-level effects of kinase inhibitors modulate TNF-α-induced apoptosis in the intestinal epithelium

Network-level effects of kinase inhibitors modulate TNF-α-induced apoptosis in the intestinal epithelium

Individual signaling pathways operate in the context of the broader signaling network. Thus, the response of a cell to signals from the environment is affected by the state of the signaling network, such as the clinically relevant example of whether some components in the network are inhibited. The...

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Bibliographic Details
Main Authors: Gierut, J. J., Lau, K. S., Lin, Y.-J., Genetti, C., Samatar, A. A., Haigis, K. M., Wood, Levi Benjamin, Lauffenburger, Douglas A
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: American Association for the Advancement of Science (AAAS) 2017
Online Access:http://hdl.handle.net/1721.1/106939

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