Inactivation of Bacteria by Electric Current in the Presence of Carbon Nanotubes Embedded Within a Polymeric Membrane
Uniform conductive composite membranes were prepared using a phase inversion method by blending carboxyl-functionalized multi-walled carbon nanotubes (CNTs) with a polysulfone polymer. At 6 % of the embedded CNTs, the membrane pore size measured by transmission electron microscopy (TEM) was approxim...
| Main Authors: | , , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | English |
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Springer US
2017
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| Online Access: | http://hdl.handle.net/1721.1/106969 https://orcid.org/0000-0003-3830-714X |
| _version_ | 1811080922580123648 |
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| author | Long, Feng Zhu, Anna Su, Erzheng Liu, Harris K. Klibanov, Alexander M |
| author2 | Massachusetts Institute of Technology. Department of Biological Engineering |
| author_facet | Massachusetts Institute of Technology. Department of Biological Engineering Long, Feng Zhu, Anna Su, Erzheng Liu, Harris K. Klibanov, Alexander M |
| author_sort | Long, Feng |
| collection | MIT |
| description | Uniform conductive composite membranes were prepared using a phase inversion method by blending carboxyl-functionalized multi-walled carbon nanotubes (CNTs) with a polysulfone polymer. At 6 % of the embedded CNTs, the membrane pore size measured by transmission electron microscopy (TEM) was approximately 50 nm. Electric current in the presence of the composite membranes markedly inactivated the model pathogenic bacteria Escherichia coli and Staphylococcus aureus, with the extent of bacterial inactivation rising when the current was increased. Over 99.999 % inactivation of both bacteria was observed in deionized water after 40 min at 5 mA direct current (DC); importantly, no appreciable inactivation occurred in the absence of either the electric field or the CNTs within the membranes under otherwise the same conditions. A much lower, although still pronounced, inactivation was seen with alternating current (AC) in a 25 mM NaCl aqueous solution. |
| first_indexed | 2024-09-23T11:38:59Z |
| format | Article |
| id | mit-1721.1/106969 |
| institution | Massachusetts Institute of Technology |
| language | English |
| last_indexed | 2024-09-23T11:38:59Z |
| publishDate | 2017 |
| publisher | Springer US |
| record_format | dspace |
| spelling | mit-1721.1/1069692022-10-01T05:02:20Z Inactivation of Bacteria by Electric Current in the Presence of Carbon Nanotubes Embedded Within a Polymeric Membrane Long, Feng Zhu, Anna Su, Erzheng Liu, Harris K. Klibanov, Alexander M Massachusetts Institute of Technology. Department of Biological Engineering Massachusetts Institute of Technology. Department of Chemistry Zhu, Anna Su, Erzheng Liu, Harris K. Klibanov, Alexander M Uniform conductive composite membranes were prepared using a phase inversion method by blending carboxyl-functionalized multi-walled carbon nanotubes (CNTs) with a polysulfone polymer. At 6 % of the embedded CNTs, the membrane pore size measured by transmission electron microscopy (TEM) was approximately 50 nm. Electric current in the presence of the composite membranes markedly inactivated the model pathogenic bacteria Escherichia coli and Staphylococcus aureus, with the extent of bacterial inactivation rising when the current was increased. Over 99.999 % inactivation of both bacteria was observed in deionized water after 40 min at 5 mA direct current (DC); importantly, no appreciable inactivation occurred in the absence of either the electric field or the CNTs within the membranes under otherwise the same conditions. A much lower, although still pronounced, inactivation was seen with alternating current (AC) in a 25 mM NaCl aqueous solution. Skolkovo Foundation (Infectious Diseases Research Center at MIT) National Natural Science Foundation of China (21277173) 2017-02-16T17:48:05Z 2017-02-16T17:48:05Z 2014-10 2014-08 2016-05-23T12:17:43Z Article http://purl.org/eprint/type/JournalArticle 0273-2289 1559-0291 http://hdl.handle.net/1721.1/106969 Zhu, Anna, Harris K. Liu, Feng Long, Erzheng Su, and Alexander M. Klibanov. “Inactivation of Bacteria by Electric Current in the Presence of Carbon Nanotubes Embedded Within a Polymeric Membrane.” Applied Biochemistry and Biotechnology 175, no. 2 (October 24, 2014): 666–676. https://orcid.org/0000-0003-3830-714X en http://dx.doi.org/10.1007/s12010-014-1318-z Applied Biochemistry and Biotechnology Creative Commons Attribution-Noncommercial-Share Alike http://creativecommons.org/licenses/by-nc-sa/4.0/ Springer Science+Business Media New York application/pdf Springer US Springer US |
| spellingShingle | Long, Feng Zhu, Anna Su, Erzheng Liu, Harris K. Klibanov, Alexander M Inactivation of Bacteria by Electric Current in the Presence of Carbon Nanotubes Embedded Within a Polymeric Membrane |
| title | Inactivation of Bacteria by Electric Current in the Presence of Carbon Nanotubes Embedded Within a Polymeric Membrane |
| title_full | Inactivation of Bacteria by Electric Current in the Presence of Carbon Nanotubes Embedded Within a Polymeric Membrane |
| title_fullStr | Inactivation of Bacteria by Electric Current in the Presence of Carbon Nanotubes Embedded Within a Polymeric Membrane |
| title_full_unstemmed | Inactivation of Bacteria by Electric Current in the Presence of Carbon Nanotubes Embedded Within a Polymeric Membrane |
| title_short | Inactivation of Bacteria by Electric Current in the Presence of Carbon Nanotubes Embedded Within a Polymeric Membrane |
| title_sort | inactivation of bacteria by electric current in the presence of carbon nanotubes embedded within a polymeric membrane |
| url | http://hdl.handle.net/1721.1/106969 https://orcid.org/0000-0003-3830-714X |
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