Advances in electrospun carbon fiber-based electrochemical sensing platforms for bioanalytical applications

Electrochemical sensing is an efficient and inexpensive method for detection of a range of chemicals of biological, clinical, and environmental interest. Carbon materials-based electrodes are commonly employed for the development of electrochemical sensors because of their low cost, biocompatibility...

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Bibliographic Details
Main Authors: Mao, Xianwen, Hatton, Trevor Alan, Tian, Wenda, Rutledge, Gregory C
Other Authors: Massachusetts Institute of Technology. Department of Chemical Engineering
Format: Article
Language:English
Published: Springer Berlin Heidelberg 2017
Online Access:http://hdl.handle.net/1721.1/107163
https://orcid.org/0000-0003-0879-6018
https://orcid.org/0000-0002-4558-245X
https://orcid.org/0000-0002-3318-6038
https://orcid.org/0000-0001-8137-1732
Description
Summary:Electrochemical sensing is an efficient and inexpensive method for detection of a range of chemicals of biological, clinical, and environmental interest. Carbon materials-based electrodes are commonly employed for the development of electrochemical sensors because of their low cost, biocompatibility, and facile electron transfer kinetics. Electrospun carbon fibers (ECFs), prepared by electrospinning of a polymeric precursor and subsequent thermal treatment, have emerged as promising carbon systems for biosensing applications since the electrochemical properties of these carbon fibers can be easily modified by processing conditions and post-treatment. This review addresses recent progress in the use of ECFs for sensor fabrication and analyte detection. We focus on the modification strategies of ECFs and identification of the key components that impart the bioelectroanalytical activities, and point out the future challenges that must be addressed in order to advance the fundamental understanding of the ECF electrochemistry and to realize the practical applications of ECF-based sensing devices.