EGLN1 Inhibition and Rerouting of α-Ketoglutarate Suffice for Remote Ischemic Protection

Ischemic preconditioning is the phenomenon whereby brief periods of sublethal ischemia protect against a subsequent, more prolonged, ischemic insult. In remote ischemic preconditioning (RIPC), ischemia to one organ protects others organs at a distance. We created mouse models to ask if inhibition of...

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Main Authors: Olenchock, Benjamin A., Moslehi, Javid, Baik, Alan H., Williams, Jeremy, Gibson, William J., Chakraborty, Abhishek A., Pierce, Kerry A., Miller, Christine M., Hanse, Eric A., Kelekar, Ameeta, Wagers, Amy J., Clish, Clary B., Kaelin, William G., Davidson, Shawn M, Sullivan, Lucas Bryan, Vander Heiden, Matthew G.
其他作者: Koch Institute for Integrative Cancer Research at MIT
格式: 文件
语言:en_US
出版: Elsevier 2017
在线阅读:http://hdl.handle.net/1721.1/107249
https://orcid.org/0000-0002-6745-8222
https://orcid.org/0000-0002-6702-4192