EGLN1 Inhibition and Rerouting of α-Ketoglutarate Suffice for Remote Ischemic Protection

EGLN1 Inhibition and Rerouting of α-Ketoglutarate Suffice for Remote Ischemic Protection

Ischemic preconditioning is the phenomenon whereby brief periods of sublethal ischemia protect against a subsequent, more prolonged, ischemic insult. In remote ischemic preconditioning (RIPC), ischemia to one organ protects others organs at a distance. We created mouse models to ask if inhibition of...

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Bibliographic Details
Main Authors: Olenchock, Benjamin A., Moslehi, Javid, Baik, Alan H., Williams, Jeremy, Gibson, William J., Chakraborty, Abhishek A., Pierce, Kerry A., Miller, Christine M., Hanse, Eric A., Kelekar, Ameeta, Wagers, Amy J., Clish, Clary B., Kaelin, William G., Davidson, Shawn M, Sullivan, Lucas Bryan, Vander Heiden, Matthew G.
Other Authors: Koch Institute for Integrative Cancer Research at MIT
Format: Article
Language:en_US
Published: Elsevier 2017
Online Access:http://hdl.handle.net/1721.1/107249
https://orcid.org/0000-0002-6745-8222
https://orcid.org/0000-0002-6702-4192

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