Novel genomic island modifies DNA with 7-deazaguanine derivatives

Novel genomic island modifies DNA with 7-deazaguanine derivatives

The discovery of ∼20-kb gene clusters containing a family of paralogs of tRNA guanosine transglycosylase genes, called tgtA5, alongside 7-cyano-7-deazaguanine (preQ[subscript 0]) synthesis and DNA metabolism genes, led to the hypothesis that 7-deazaguanine derivatives are inserted in DNA. This was e...

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Bibliographic Details
Main Authors: Thiaville, Jennifer J., Yuan, Yifeng, Hutinet, Geoffrey, Thiaville, Patrick C., Brochier-Armanet, Celine, Letarov, Andrey V., Malik, Chanchal K., Rizzo, Carmelo J., de Crécy-Lagard, Valérie, Kellner, Stefanie M, Jumpathong, Watthanachai, Mohapatra, Susovan, Hillebrand, Roman, Dedon, Peter C
Other Authors: Massachusetts Institute of Technology. Center for Environmental Health Sciences
Format: Article
Language:en_US
Published: National Academy of Sciences (U.S.) 2017
Online Access:http://hdl.handle.net/1721.1/107419
https://orcid.org/0000-0003-3224-7502
https://orcid.org/0000-0002-1976-8103
https://orcid.org/0000-0001-9357-0077
https://orcid.org/0000-0003-0011-3067

Internet

http://hdl.handle.net/1721.1/107419
https://orcid.org/0000-0003-3224-7502
https://orcid.org/0000-0002-1976-8103
https://orcid.org/0000-0001-9357-0077
https://orcid.org/0000-0003-0011-3067

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