PF4 Promotes Platelet Production and Lung Cancer Growth
Co-option of host components by solid tumors facilitates cancer progression and can occur in both local tumor microenvironments and remote locations. At present, the signals involved in long-distance communication remain insufficiently understood. Here, we identify platelet factor 4 (PF4, CXCL4) as...
Main Authors: | Pucci, Ferdinando, Newton, Andita P., Garris, Christopher, Nunes, Ernesto, Evavold, Charles, Pfirschke, Christina, Mino-Kenudson, Mari, Pittet, Mikael J., Engblom, Camilla, Rickelt, Steffen, Hynes, Richard O., Weissleder, Ralph |
---|---|
Other Authors: | Harvard University--MIT Division of Health Sciences and Technology |
Format: | Article |
Language: | en_US |
Published: |
2017
|
Online Access: | http://hdl.handle.net/1721.1/107431 https://orcid.org/0000-0002-5224-7764 https://orcid.org/0000-0001-7603-8396 https://orcid.org/0000-0003-0828-4143 |
Similar Items
-
Immunogenic Chemotherapy Sensitizes Tumors to Checkpoint Blockade Therapy
by: Pfirschke, Christina, et al.
Published: (2018) -
LTX-315 sequentially promotes lymphocyte-independent and lymphocyte-dependent antitumor effects
by: Hsin-Wei Liao, et al.
Published: (2019-10-01) -
Tumor-Promoting Ly-6G+ SiglecFhigh Cells Are Mature and Long-Lived Neutrophils
by: Christina Pfirschke, et al.
Published: (2020-09-01) -
Antibodies and methods for immunohistochemistry of extracellular matrix proteins
by: Rickelt, Steffen, et al.
Published: (2020) -
Osteoblasts remotely supply lung tumors with cancer-promoting SiglecF
by: Rickelt, Steffen, et al.
Published: (2018)