Tethered capsule endomicroscopy: from bench to bedside at a primary care practice

Due to the relatively high cost and inconvenience of upper endoscopic biopsy and the rising incidence of esophageal adenocarcinoma, there is currently a need for an improved method for screening for Barrett’s esophagus. Ideally, such a test would be applied in the primary care setting and patients r...

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Dades bibliogràfiques
Autors principals: Gora, Michalina J., Simmons, Leigh H., Quénéhervé, Lucille, Grant, Catriona N., Carruth, Robert W., Lu, Weina, Tiernan, Aubrey, Dong, Jing, Walker-Corkery, Beth, Soomro, Amna, Rosenberg, Mireille, Metlay, Joshua P., Tearney, Guillermo J.
Altres autors: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Idioma:en_US
Publicat: SPIE 2017
Accés en línia:http://hdl.handle.net/1721.1/107494
Descripció
Sumari:Due to the relatively high cost and inconvenience of upper endoscopic biopsy and the rising incidence of esophageal adenocarcinoma, there is currently a need for an improved method for screening for Barrett’s esophagus. Ideally, such a test would be applied in the primary care setting and patients referred to endoscopy if the result is suspicious for Barrett’s. Tethered capsule endomicroscopy (TCE) is a recently developed technology that rapidly acquires microscopic images of the entire esophagus in unsedated subjects. Here, we present our first experience with clinical translation and feasibility of TCE in a primary care practice. The acceptance of the TCE device by the primary care clinical staff and patients shows the potential of this device to be useful as a screening tool for a broader population.