Tethered capsule endomicroscopy: from bench to bedside at a primary care practice

Due to the relatively high cost and inconvenience of upper endoscopic biopsy and the rising incidence of esophageal adenocarcinoma, there is currently a need for an improved method for screening for Barrett’s esophagus. Ideally, such a test would be applied in the primary care setting and patients r...

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Main Authors: Gora, Michalina J., Simmons, Leigh H., Quénéhervé, Lucille, Grant, Catriona N., Carruth, Robert W., Lu, Weina, Tiernan, Aubrey, Dong, Jing, Walker-Corkery, Beth, Soomro, Amna, Rosenberg, Mireille, Metlay, Joshua P., Tearney, Guillermo J.
Other Authors: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Language:en_US
Published: SPIE 2017
Online Access:http://hdl.handle.net/1721.1/107494
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author Gora, Michalina J.
Simmons, Leigh H.
Quénéhervé, Lucille
Grant, Catriona N.
Carruth, Robert W.
Lu, Weina
Tiernan, Aubrey
Dong, Jing
Walker-Corkery, Beth
Soomro, Amna
Rosenberg, Mireille
Metlay, Joshua P.
Tearney, Guillermo J.
author2 Harvard University--MIT Division of Health Sciences and Technology
author_facet Harvard University--MIT Division of Health Sciences and Technology
Gora, Michalina J.
Simmons, Leigh H.
Quénéhervé, Lucille
Grant, Catriona N.
Carruth, Robert W.
Lu, Weina
Tiernan, Aubrey
Dong, Jing
Walker-Corkery, Beth
Soomro, Amna
Rosenberg, Mireille
Metlay, Joshua P.
Tearney, Guillermo J.
author_sort Gora, Michalina J.
collection MIT
description Due to the relatively high cost and inconvenience of upper endoscopic biopsy and the rising incidence of esophageal adenocarcinoma, there is currently a need for an improved method for screening for Barrett’s esophagus. Ideally, such a test would be applied in the primary care setting and patients referred to endoscopy if the result is suspicious for Barrett’s. Tethered capsule endomicroscopy (TCE) is a recently developed technology that rapidly acquires microscopic images of the entire esophagus in unsedated subjects. Here, we present our first experience with clinical translation and feasibility of TCE in a primary care practice. The acceptance of the TCE device by the primary care clinical staff and patients shows the potential of this device to be useful as a screening tool for a broader population.
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spelling mit-1721.1/1074942022-09-29T13:49:38Z Tethered capsule endomicroscopy: from bench to bedside at a primary care practice Gora, Michalina J. Simmons, Leigh H. Quénéhervé, Lucille Grant, Catriona N. Carruth, Robert W. Lu, Weina Tiernan, Aubrey Dong, Jing Walker-Corkery, Beth Soomro, Amna Rosenberg, Mireille Metlay, Joshua P. Tearney, Guillermo J. Harvard University--MIT Division of Health Sciences and Technology Tearney, Guillermo J. Due to the relatively high cost and inconvenience of upper endoscopic biopsy and the rising incidence of esophageal adenocarcinoma, there is currently a need for an improved method for screening for Barrett’s esophagus. Ideally, such a test would be applied in the primary care setting and patients referred to endoscopy if the result is suspicious for Barrett’s. Tethered capsule endomicroscopy (TCE) is a recently developed technology that rapidly acquires microscopic images of the entire esophagus in unsedated subjects. Here, we present our first experience with clinical translation and feasibility of TCE in a primary care practice. The acceptance of the TCE device by the primary care clinical staff and patients shows the potential of this device to be useful as a screening tool for a broader population. National Institutes of Health (U.S.) (Grant 1 R01 DK100569- 01A1) Massachusetts General Hospital. Research Scholars Program John and Dottie Remondi 2017-03-20T15:14:22Z 2017-03-20T15:14:22Z 2016-10 2016-06 Article http://purl.org/eprint/type/JournalArticle 1083-3668 http://hdl.handle.net/1721.1/107494 Gora, Michalina J. et al. “Tethered Capsule Endomicroscopy: From Bench to Bedside at a Primary Care Practice.” Journal of Biomedical Optics 21.10 (2016): 104001. en_US http://dx.doi.org/10.1117/1.jbo.21.10.104001 Journal of Biomedical Optics Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use. application/pdf SPIE SPIE
spellingShingle Gora, Michalina J.
Simmons, Leigh H.
Quénéhervé, Lucille
Grant, Catriona N.
Carruth, Robert W.
Lu, Weina
Tiernan, Aubrey
Dong, Jing
Walker-Corkery, Beth
Soomro, Amna
Rosenberg, Mireille
Metlay, Joshua P.
Tearney, Guillermo J.
Tethered capsule endomicroscopy: from bench to bedside at a primary care practice
title Tethered capsule endomicroscopy: from bench to bedside at a primary care practice
title_full Tethered capsule endomicroscopy: from bench to bedside at a primary care practice
title_fullStr Tethered capsule endomicroscopy: from bench to bedside at a primary care practice
title_full_unstemmed Tethered capsule endomicroscopy: from bench to bedside at a primary care practice
title_short Tethered capsule endomicroscopy: from bench to bedside at a primary care practice
title_sort tethered capsule endomicroscopy from bench to bedside at a primary care practice
url http://hdl.handle.net/1721.1/107494
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