Noncontact three-dimensional mapping of intracellular hydromechanical properties by Brillouin microscopy

Current measurements of the biomechanical properties of cells require physical contact with cells or lack subcellular resolution. Here we developed a label-free microscopy technique based on Brillouin light scattering that is capable of measuring an intracellular longitudinal modulus with optical re...

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Bibliographic Details
Main Authors: Scarcelli, Giuliano, Patel, Kripa, Polacheck III, William Joseph, Tavakoli Nia, Hadi, Grodzinsky, Alan J, Kamm, Roger Dale, Yun, Seok Hyun (Andy)
Other Authors: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Language:en_US
Published: Nature Publishing Group 2017
Online Access:http://hdl.handle.net/1721.1/107616
https://orcid.org/0000-0003-2728-0746
https://orcid.org/0000-0003-1970-9901
https://orcid.org/0000-0002-4942-3456
https://orcid.org/0000-0002-7232-304X