Magnitude and Kinetics of CD8[superscript +] T Cell Activation during Hyperacute HIV Infection Impact Viral Set Point

Magnitude and Kinetics of CD8[superscript +] T Cell Activation during Hyperacute HIV Infection Impact Viral Set Point

CD8[superscript +] T cells contribute to the control of HIV, but it is not clear whether initial immune responses modulate the viral set point. We screened high-risk uninfected women twice a week for plasma HIV RNA and identified 12 hyperacute infections. Onset of viremia elicited a massive HIV-spec...

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Bibliographic Details
Main Authors: Ndhlovu, Zaza M., Kamya, Philomena, Mewalal, Nikoshia, Kløverpris, Henrik N., Nkosi, Thandeka, Pretorius, Karyn, Laher, Faatima, Ogunshola, Funsho, Chopera, Denis, Ghebremichael, Musie, Ismail, Nasreen, Moodley, Amber, Malik, Amna, Leslie, Alasdair, Goulder, Philip J.R., Buus, Søren, Dong, Krista, Ndung’u, Thumbi, Walker, Bruce D., Chakraborty, Arup K, Shekhar, Karthik
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Format: Article
Language:en_US
Published: Elsevier/Cell Press 2017
Online Access:http://hdl.handle.net/1721.1/107652
https://orcid.org/0000-0003-1268-9602

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