Poised chromatin in the mammalian germ line
Poised (bivalent) chromatin is defined by the simultaneous presence of histone modifications associated with both gene activation and repression. This epigenetic feature was first observed at promoters of lineage-specific regulatory genes in embryonic stem cells in culture. More recent work has show...
Main Authors: | Lesch, B. J., Page, David C |
---|---|
Other Authors: | Massachusetts Institute of Technology. Department of Biology |
Format: | Article |
Language: | en_US |
Published: |
Company of Biologists
2017
|
Online Access: | http://hdl.handle.net/1721.1/107653 https://orcid.org/0000-0001-9920-3411 |
Similar Items
-
A set of genes critical to development is epigenetically poised in mouse germ cells from fetal stages through completion of meiosis
by: Lesch, Bluma J., et al.
Published: (2014) -
Genetics of germ cell development
by: Lesch, Bluma J., et al.
Published: (2014) -
Parallel evolution of male germline epigenetic poising and somatic development in animals
by: Lesch, Bluma J, et al.
Published: (2017) -
Mammalian germ cells are determined after PGC colonization of the nascent gonad
by: Nicholls, Peter K., et al.
Published: (2020) -
The Ligand Binding Domain of GCNF Is Not Required for Repression of Pluripotency Genes in Mouse Fetal Ovarian Germ Cells
by: Okumura, Leah M., et al.
Published: (2013)