Structural basis for chemokine recognition and activation of a viral G protein-coupled receptor

Structural basis for chemokine recognition and activation of a viral G protein-coupled receptor

Chemokines are small proteins that function as immune modulators through activation of chemokine G protein–coupled receptors (GPCRs). Several viruses also encode chemokines and chemokine receptors to subvert the host immune response. How protein ligands activate GPCRs remains unknown. We report the...

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Bibliographic Details
Main Authors:	Burg, J. S., Ingram, J. R., Venkatakrishnan, A. J., Jude, K. M., Dukkipati, A., Feinberg, E. N., Waghray, D., Dror, R. O., Garcia, K. C., Angelini, Alessandro, Ploegh, Hidde
Other Authors:	Massachusetts Institute of Technology. Department of Biology
Format:	Article
Language:	en_US
Published:	American Association for the Advancement of Science (AAAS) 2017
Online Access:	http://hdl.handle.net/1721.1/107655 https://orcid.org/0000-0001-5923-3843 https://orcid.org/0000-0002-1090-6071

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