Structural basis for chemokine recognition and activation of a viral G protein-coupled receptor
Chemokines are small proteins that function as immune modulators through activation of chemokine G protein–coupled receptors (GPCRs). Several viruses also encode chemokines and chemokine receptors to subvert the host immune response. How protein ligands activate GPCRs remains unknown. We report the...
Main Authors: | Burg, J. S., Ingram, J. R., Venkatakrishnan, A. J., Jude, K. M., Dukkipati, A., Feinberg, E. N., Waghray, D., Dror, R. O., Garcia, K. C., Angelini, Alessandro, Ploegh, Hidde |
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Other Authors: | Massachusetts Institute of Technology. Department of Biology |
Format: | Article |
Language: | en_US |
Published: |
American Association for the Advancement of Science (AAAS)
2017
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Online Access: | http://hdl.handle.net/1721.1/107655 https://orcid.org/0000-0001-5923-3843 https://orcid.org/0000-0002-1090-6071 |
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