Molecular basis of cobalamin-dependent RNA modification
Queuosine (Q) was discovered in the wobble position of a transfer RNA (tRNA) 47 years ago, yet the final biosynthetic enzyme responsible for Q-maturation, epoxyqueuosine (oQ) reductase (QueG), was only recently identified. QueG is a cobalamin (Cbl)-dependent, [4Fe-4S] cluster-containing protein that...
Main Authors: | Miles, Zachary D., Maiocco, Stephanie J., Elliott, Sean J., Bandarian, Vahe, Dowling, Daniel P., Koehrer, Caroline, Drennan, Catherine L. |
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Other Authors: | Massachusetts Institute of Technology. Department of Biology |
Format: | Article |
Language: | en_US |
Published: |
Oxford University Press
2017
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Online Access: | http://hdl.handle.net/1721.1/107678 https://orcid.org/0000-0001-5486-2755 |
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