Neuroprotection and acidosis induced by cortical spreading depression
We read with interest the article “Cortical spreading depression produces a neuroprotective effect activating mitochondrial uncoupling protein-5” published in Neuropsychiatr Dis Treat by Viggiano et al.1 The authors showed that cerebral spreading depression (CSD) triggered uncoupling protein-5 (UCP-...
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| Format: | Article |
| Language: | en_US |
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Dove Medical Press
2017
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| Online Access: | http://hdl.handle.net/1721.1/107754 |
| _version_ | 1826195959439163392 |
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| author | Chan, Suk-tak Kwong, Kenneth K |
| author2 | Harvard University--MIT Division of Health Sciences and Technology |
| author_facet | Harvard University--MIT Division of Health Sciences and Technology Chan, Suk-tak Kwong, Kenneth K |
| author_sort | Chan, Suk-tak |
| collection | MIT |
| description | We read with interest the article “Cortical spreading depression produces a neuroprotective effect activating mitochondrial uncoupling protein-5” published in Neuropsychiatr Dis Treat by Viggiano et al.1 The authors showed that cerebral spreading depression (CSD) triggered uncoupling protein-5 (UCP-5),1 which had been reported to exert a long-term effect upon neuron protection.2 The result is another piece in CSD literature on modifying gene expressions to provide neuroprotection to subsequent ischemic episodes.3,4 |
| first_indexed | 2024-09-23T10:18:33Z |
| format | Article |
| id | mit-1721.1/107754 |
| institution | Massachusetts Institute of Technology |
| language | en_US |
| last_indexed | 2024-09-23T10:18:33Z |
| publishDate | 2017 |
| publisher | Dove Medical Press |
| record_format | dspace |
| spelling | mit-1721.1/1077542022-09-26T17:08:48Z Neuroprotection and acidosis induced by cortical spreading depression Chan, Suk-tak Kwong, Kenneth K Harvard University--MIT Division of Health Sciences and Technology Kwong, Kenneth K We read with interest the article “Cortical spreading depression produces a neuroprotective effect activating mitochondrial uncoupling protein-5” published in Neuropsychiatr Dis Treat by Viggiano et al.1 The authors showed that cerebral spreading depression (CSD) triggered uncoupling protein-5 (UCP-5),1 which had been reported to exert a long-term effect upon neuron protection.2 The result is another piece in CSD literature on modifying gene expressions to provide neuroprotection to subsequent ischemic episodes.3,4 2017-03-28T15:56:42Z 2017-03-28T15:56:42Z 2016-12 2016-10 Article http://purl.org/eprint/type/JournalArticle 1178-2021 http://hdl.handle.net/1721.1/107754 Kwong, Kenneth, and Suk-tak Chan. “Neuroprotection and Acidosis Induced by Cortical Spreading Depression.” Neuropsychiatric Disease and Treatment Volume 12 (2016): 3191–3194. en_US http://dx.doi.org/10.2147/ndt.s125677 Neuropsychiatric Disease and Treatment Creative Commons Attribution-NonCommercial 3.0 Unported https://creativecommons.org/licenses/by-nc/3.0/ application/pdf Dove Medical Press Dove Medical Press |
| spellingShingle | Chan, Suk-tak Kwong, Kenneth K Neuroprotection and acidosis induced by cortical spreading depression |
| title | Neuroprotection and acidosis induced by cortical spreading depression |
| title_full | Neuroprotection and acidosis induced by cortical spreading depression |
| title_fullStr | Neuroprotection and acidosis induced by cortical spreading depression |
| title_full_unstemmed | Neuroprotection and acidosis induced by cortical spreading depression |
| title_short | Neuroprotection and acidosis induced by cortical spreading depression |
| title_sort | neuroprotection and acidosis induced by cortical spreading depression |
| url | http://hdl.handle.net/1721.1/107754 |
| work_keys_str_mv | AT chansuktak neuroprotectionandacidosisinducedbycorticalspreadingdepression AT kwongkennethk neuroprotectionandacidosisinducedbycorticalspreadingdepression |