A toolbox of Cre-dependent optogenetic transgenic mice for light-induced activation and silencing

We report on wide-field optically detected magnetic resonance imaging of nitrogen-vacancy centers (NVs) in type IIa polycrystalline diamond. These studies reveal a heterogeneous crystalline environment that produces a varied density of NV centers, including preferential orientation within some indi...

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Podrobná bibliografie
Hlavní autoři:	Madisen, Linda, Mao, Tianyi, Koch, Henner, Zhuo, Jia-min, Berenyi, Antal, Fujisawa, Shigeyoshi, Hsu, Yun-Wei A, Garcia, Alfredo J, Gu, Xuan, Zanella, Sebastien, Kidney, Jolene, Gu, Hong, Mao, Yimei, Hooks, Bryan M, Buzsáki, György, Ramirez, Jan Marino, Jones, Allan R, Svoboda, Karel, Han, Xue, Turner, Eric E, Zeng, Hongkui, Boyden, Edward
Další autoři:	Massachusetts Institute of Technology. Media Laboratory
Médium:	Článek
Jazyk:	en_US
Vydáno:	Nature Publishing Group 2017
On-line přístup:	http://hdl.handle.net/1721.1/107771 https://orcid.org/0000-0002-0419-3351

Popis
Shrnutí:	We report on wide-field optically detected magnetic resonance imaging of nitrogen-vacancy centers (NVs) in type IIa polycrystalline diamond. These studies reveal a heterogeneous crystalline environment that produces a varied density of NV centers, including preferential orientation within some individual crystal grains, but preserves long spin coherence times. Using the native NVs as nanoscale sensors, we introduce a three-dimensional strain imaging technique with high sensitivity (<10[superscript -5] Hz[superscript –1/2]) and diffraction-limited resolution across a wide field of view.

A toolbox of Cre-dependent optogenetic transgenic mice for light-induced activation and silencing

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