A toolbox of Cre-dependent optogenetic transgenic mice for light-induced activation and silencing

We report on wide-field optically detected magnetic resonance imaging of nitrogen-vacancy centers (NVs) in type IIa polycrystalline diamond. These studies reveal a heterogeneous crystalline environment that produces a varied density of NV centers, including preferential orientation within some indi...

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Main Authors: Madisen, Linda, Mao, Tianyi, Koch, Henner, Zhuo, Jia-min, Berenyi, Antal, Fujisawa, Shigeyoshi, Hsu, Yun-Wei A, Garcia, Alfredo J, Gu, Xuan, Zanella, Sebastien, Kidney, Jolene, Gu, Hong, Mao, Yimei, Hooks, Bryan M, Buzsáki, György, Ramirez, Jan Marino, Jones, Allan R, Svoboda, Karel, Han, Xue, Turner, Eric E, Zeng, Hongkui, Boyden, Edward
其他作者: Massachusetts Institute of Technology. Media Laboratory
格式: 文件
语言:en_US
出版: Nature Publishing Group 2017
在线阅读:http://hdl.handle.net/1721.1/107771
https://orcid.org/0000-0002-0419-3351
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author Madisen, Linda
Mao, Tianyi
Koch, Henner
Zhuo, Jia-min
Berenyi, Antal
Fujisawa, Shigeyoshi
Hsu, Yun-Wei A
Garcia, Alfredo J
Gu, Xuan
Zanella, Sebastien
Kidney, Jolene
Gu, Hong
Mao, Yimei
Hooks, Bryan M
Buzsáki, György
Ramirez, Jan Marino
Jones, Allan R
Svoboda, Karel
Han, Xue
Turner, Eric E
Zeng, Hongkui
Boyden, Edward
author2 Massachusetts Institute of Technology. Media Laboratory
author_facet Massachusetts Institute of Technology. Media Laboratory
Madisen, Linda
Mao, Tianyi
Koch, Henner
Zhuo, Jia-min
Berenyi, Antal
Fujisawa, Shigeyoshi
Hsu, Yun-Wei A
Garcia, Alfredo J
Gu, Xuan
Zanella, Sebastien
Kidney, Jolene
Gu, Hong
Mao, Yimei
Hooks, Bryan M
Buzsáki, György
Ramirez, Jan Marino
Jones, Allan R
Svoboda, Karel
Han, Xue
Turner, Eric E
Zeng, Hongkui
Boyden, Edward
author_sort Madisen, Linda
collection MIT
description We report on wide-field optically detected magnetic resonance imaging of nitrogen-vacancy centers (NVs) in type IIa polycrystalline diamond. These studies reveal a heterogeneous crystalline environment that produces a varied density of NV centers, including preferential orientation within some individual crystal grains, but preserves long spin coherence times. Using the native NVs as nanoscale sensors, we introduce a three-dimensional strain imaging technique with high sensitivity (<10[superscript -5] Hz[superscript –1/2]) and diffraction-limited resolution across a wide field of view.
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spelling mit-1721.1/1077712022-09-28T11:29:24Z A toolbox of Cre-dependent optogenetic transgenic mice for light-induced activation and silencing Madisen, Linda Mao, Tianyi Koch, Henner Zhuo, Jia-min Berenyi, Antal Fujisawa, Shigeyoshi Hsu, Yun-Wei A Garcia, Alfredo J Gu, Xuan Zanella, Sebastien Kidney, Jolene Gu, Hong Mao, Yimei Hooks, Bryan M Buzsáki, György Ramirez, Jan Marino Jones, Allan R Svoboda, Karel Han, Xue Turner, Eric E Zeng, Hongkui Boyden, Edward Massachusetts Institute of Technology. Media Laboratory Boyden, Edward We report on wide-field optically detected magnetic resonance imaging of nitrogen-vacancy centers (NVs) in type IIa polycrystalline diamond. These studies reveal a heterogeneous crystalline environment that produces a varied density of NV centers, including preferential orientation within some individual crystal grains, but preserves long spin coherence times. Using the native NVs as nanoscale sensors, we introduce a three-dimensional strain imaging technique with high sensitivity (<10[superscript -5] Hz[superscript –1/2]) and diffraction-limited resolution across a wide field of view. Allen Institute for Brain Science Howard Hughes Medical Institute 2017-03-29T20:23:48Z 2017-03-29T20:23:48Z 2012-03 2011-12 Article http://purl.org/eprint/type/JournalArticle 1097-6256 1546-1726 http://hdl.handle.net/1721.1/107771 Madisen, Linda et al. “A Toolbox of Cre-Dependent Optogenetic Transgenic Mice for Light-Induced Activation and Silencing.” Nature Neuroscience 15.5 (2012): 793–802. https://orcid.org/0000-0002-0419-3351 en_US http://dx.doi.org/10.1038/nn.3078 Nature Neuroscience Creative Commons Attribution-Noncommercial-Share Alike http://creativecommons.org/licenses/by-nc-sa/4.0/ application/pdf Nature Publishing Group PMC
spellingShingle Madisen, Linda
Mao, Tianyi
Koch, Henner
Zhuo, Jia-min
Berenyi, Antal
Fujisawa, Shigeyoshi
Hsu, Yun-Wei A
Garcia, Alfredo J
Gu, Xuan
Zanella, Sebastien
Kidney, Jolene
Gu, Hong
Mao, Yimei
Hooks, Bryan M
Buzsáki, György
Ramirez, Jan Marino
Jones, Allan R
Svoboda, Karel
Han, Xue
Turner, Eric E
Zeng, Hongkui
Boyden, Edward
A toolbox of Cre-dependent optogenetic transgenic mice for light-induced activation and silencing
title A toolbox of Cre-dependent optogenetic transgenic mice for light-induced activation and silencing
title_full A toolbox of Cre-dependent optogenetic transgenic mice for light-induced activation and silencing
title_fullStr A toolbox of Cre-dependent optogenetic transgenic mice for light-induced activation and silencing
title_full_unstemmed A toolbox of Cre-dependent optogenetic transgenic mice for light-induced activation and silencing
title_short A toolbox of Cre-dependent optogenetic transgenic mice for light-induced activation and silencing
title_sort toolbox of cre dependent optogenetic transgenic mice for light induced activation and silencing
url http://hdl.handle.net/1721.1/107771
https://orcid.org/0000-0002-0419-3351
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