Is antibacterial PNA the answer for combating multidrug resistant bacterial infections?
The emergence of multidrug resistant bacterial infections is a serious problem. Treatment options are limited to patients those are infected with multidrug resistant bacteria. We are in a desperate need of new antibiotics. Antisense oligomers of PNA (Peptide Nucleic Acid) were introduced in late 90’...
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| Other Authors: | |
| Format: | Article |
| Language: | en_US |
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International Network for Natural Sciences (INNSPUB)
2017
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| Online Access: | http://hdl.handle.net/1721.1/107894 https://orcid.org/0000-0002-8465-3433 |
| _version_ | 1811082050752479232 |
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| author | Ghosal, Anubrata |
| author2 | Massachusetts Institute of Technology. Department of Biology |
| author_facet | Massachusetts Institute of Technology. Department of Biology Ghosal, Anubrata |
| author_sort | Ghosal, Anubrata |
| collection | MIT |
| description | The emergence of multidrug resistant bacterial infections is a serious problem. Treatment options are limited to patients those are infected with multidrug resistant bacteria. We are in a desperate need of new antibiotics. Antisense oligomers of PNA (Peptide Nucleic Acid) were introduced in late 90’s as antibacterial agents in an intention to create a new class of bacterial specific antibiotic. Followed by several studies have demonstrated that antibacterial PNA oligomers are effective in a verity of pathogenic bacterial strains. Development of PNA-based drugs (PNA antibiotics) will help us to combat infections of drug resistant bacterial strains. |
| first_indexed | 2024-09-23T11:56:39Z |
| format | Article |
| id | mit-1721.1/107894 |
| institution | Massachusetts Institute of Technology |
| language | en_US |
| last_indexed | 2024-09-23T11:56:39Z |
| publishDate | 2017 |
| publisher | International Network for Natural Sciences (INNSPUB) |
| record_format | dspace |
| spelling | mit-1721.1/1078942022-09-27T23:01:13Z Is antibacterial PNA the answer for combating multidrug resistant bacterial infections? Ghosal, Anubrata Massachusetts Institute of Technology. Department of Biology Ghosal, Anubrata The emergence of multidrug resistant bacterial infections is a serious problem. Treatment options are limited to patients those are infected with multidrug resistant bacteria. We are in a desperate need of new antibiotics. Antisense oligomers of PNA (Peptide Nucleic Acid) were introduced in late 90’s as antibacterial agents in an intention to create a new class of bacterial specific antibiotic. Followed by several studies have demonstrated that antibacterial PNA oligomers are effective in a verity of pathogenic bacterial strains. Development of PNA-based drugs (PNA antibiotics) will help us to combat infections of drug resistant bacterial strains. 2017-04-06T14:52:18Z 2017-04-06T14:52:18Z 2017-01 Article http://purl.org/eprint/type/JournalArticle 22206655 22225234 http://hdl.handle.net/1721.1/107894 Ghosal, Anubrata. “Is Antibacterial PNA the Answer for Combating Multidrug Resistant Bacterial Infections?” International Journal of Biosciences (IJB) 10, no. 1 (January 31, 2017): 408-410. https://orcid.org/0000-0002-8465-3433 en_US http://dx.doi.org/10.12692/ijb/10.1.408-410 International Journal of Biosciences (IJB) Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use. application/pdf International Network for Natural Sciences (INNSPUB) Ghosal |
| spellingShingle | Ghosal, Anubrata Is antibacterial PNA the answer for combating multidrug resistant bacterial infections? |
| title | Is antibacterial PNA the answer for combating multidrug resistant bacterial infections? |
| title_full | Is antibacterial PNA the answer for combating multidrug resistant bacterial infections? |
| title_fullStr | Is antibacterial PNA the answer for combating multidrug resistant bacterial infections? |
| title_full_unstemmed | Is antibacterial PNA the answer for combating multidrug resistant bacterial infections? |
| title_short | Is antibacterial PNA the answer for combating multidrug resistant bacterial infections? |
| title_sort | is antibacterial pna the answer for combating multidrug resistant bacterial infections |
| url | http://hdl.handle.net/1721.1/107894 https://orcid.org/0000-0002-8465-3433 |
| work_keys_str_mv | AT ghosalanubrata isantibacterialpnatheanswerforcombatingmultidrugresistantbacterialinfections |