Systematic Analysis of Quantitative Logic Model Ensembles Predicts Drug Combination Effects on Cell Signaling Networks
A major challenge in developing anticancer therapies is determining the efficacies of drugs and their combinations in physiologically relevant microenvironments. We describe here our application of “constrained fuzzy logic” (CFL) ensemble modeling of the intracellular signaling network for predictin...
| Main Authors: | , , , |
|---|---|
| Outros autores: | |
| Formato: | Artigo |
| Idioma: | en_US |
| Publicado: |
Nature Publishing Group
2017
|
| Acceso en liña: | http://hdl.handle.net/1721.1/108162 |