Longer lifespan in male mice treated with a weakly estrogenic agonist, an antioxidant, an α-glucosidase inhibitor or a Nrf2-inducer

Longer lifespan in male mice treated with a weakly estrogenic agonist, an antioxidant, an α-glucosidase inhibitor or a Nrf2-inducer

The National Institute on Aging Interventions Testing Program (ITP) evaluates agents hypothesized to increase healthy lifespan in genetically heterogeneous mice. Each compound is tested in parallel at three sites, and all results are published. We report the effects of lifelong treatment of mice wit...

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Bibliographic Details
Main Authors: Strong, Randy, Miller, Richard A., Antebi, Adam, Astle, Clinton M., Bogue, Molly, Denzel, Martin S., Fernandez, Elizabeth, Flurkey, Kevin, Hamilton, Karyn L., Lamming, Dudley W., Javors, Martin A., de Magalhães, João Pedro, Martinez, Paul Anthony, McCord, Joe M., Miller, Benjamin F., Müller, Michael, Nelson, James F., Ndukum, Juliet, Rainger, G. Ed., Richardson, Arlan, Salmon, Adam B., Simpkins, James W., Steegenga, Wilma T., Nadon, Nancy L., Harrison, David E., Sabatini, David
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Wiley Blackwell 2017
Online Access:http://hdl.handle.net/1721.1/108183
https://orcid.org/0000-0002-1446-7256

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