Pneumococcal Pneumolysin Induces DNA Damage and Cell Cycle Arrest

Pneumococcal Pneumolysin Induces DNA Damage and Cell Cycle Arrest

Streptococcus pneumoniae produces pneumolysin toxin as a key virulence factor against host cells. Pneumolysin is a cholesterol-dependent cytolysin (CDC) toxin that forms lytic pores in host membranes and mediates pneumococcal disease pathogenesis by modulating inflammatory responses. Here, we show t...

Full description

Bibliographic Details
Main Authors: Kwang, Jimmy, Engelward, Bevin P, Rai, Prashant, Chow, Vincent H., He, Fang, 1956-
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: Nature Publishing Group 2017
Online Access:http://hdl.handle.net/1721.1/108369

Similar Items

Similar Items