Protein C receptor (PROCR) is a negative regulator of Th17 pathogenicity

Protein C receptor (PROCR) is a negative regulator of Th17 pathogenicity

Th17 cells are key players in defense against pathogens and maintaining tissue homeostasis, but also act as critical drivers of autoimmune diseases. Based on single-cell RNA-seq profiling of pathogenic versus nonpathogenic Th17 cells, we identified protein C receptor (PROCR) as a cell surface molecu...

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Bibliographic Details
Main Authors: Kishi, Yasuhiro, Kondo, Takaaki, Xiao, Sheng, Yosef, Nir, Gaublomme, Jellert, Wu, Chuan, Wang, Chao, Chihara, Norio, Regev, Aviv, Joller, Nicole, Kuchroo, Vijay K.
Other Authors: Broad Institute of MIT and Harvard
Format: Article
Language:en_US
Published: Rockefeller University Press, The 2017
Online Access:http://hdl.handle.net/1721.1/108596
https://orcid.org/0000-0001-8567-2049

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