Mechanisms of dynamic nuclear polarization in insulating solids
Dynamic nuclear polarization (DNP) is a technique used to enhance signal intensities in NMR experiments by transferring the high polarization of electrons to their surrounding nuclei. The past decade has witnessed a renaissance in the development of DNP, especially at high magnetic fields, and its a...
| Main Authors: | , , |
|---|---|
| Other Authors: | |
| Format: | Article |
| Language: | en_US |
| Published: |
Elsevier
2017
|
| Online Access: | http://hdl.handle.net/1721.1/108646 https://orcid.org/0000-0001-9092-612X https://orcid.org/0000-0003-1589-832X |
| _version_ | 1811068551738425344 |
|---|---|
| author | Ni, Qing Zhe Griffin, Robert Guy Can, Thach V |
| author2 | Massachusetts Institute of Technology. Department of Chemistry |
| author_facet | Massachusetts Institute of Technology. Department of Chemistry Ni, Qing Zhe Griffin, Robert Guy Can, Thach V |
| author_sort | Ni, Qing Zhe |
| collection | MIT |
| description | Dynamic nuclear polarization (DNP) is a technique used to enhance signal intensities in NMR experiments by transferring the high polarization of electrons to their surrounding nuclei. The past decade has witnessed a renaissance in the development of DNP, especially at high magnetic fields, and its application in several areas including biophysics, chemistry, structural biology and materials science. Recent technical and theoretical advances have expanded our understanding of established experiments: for example, the cross effect DNP in samples spinning at the magic angle. Furthermore, new experiments suggest that our understanding of the Overhauser effect and its applicability to insulating solids needs to be re-examined. In this article, we summarize important results of the past few years and provide quantum mechanical explanations underlying these results. We also discuss future directions of DNP and current limitations, including the problem of resolution in protein spectra recorded at 80–100 K. |
| first_indexed | 2024-09-23T07:57:41Z |
| format | Article |
| id | mit-1721.1/108646 |
| institution | Massachusetts Institute of Technology |
| language | en_US |
| last_indexed | 2024-09-23T07:57:41Z |
| publishDate | 2017 |
| publisher | Elsevier |
| record_format | dspace |
| spelling | mit-1721.1/1086462022-09-30T01:19:25Z Mechanisms of dynamic nuclear polarization in insulating solids Ni, Qing Zhe Griffin, Robert Guy Can, Thach V Massachusetts Institute of Technology. Department of Chemistry Francis Bitter Magnet Laboratory (Massachusetts Institute of Technology) Can, Thach Van Ni, Qing Zhe Griffin, Robert Guy Dynamic nuclear polarization (DNP) is a technique used to enhance signal intensities in NMR experiments by transferring the high polarization of electrons to their surrounding nuclei. The past decade has witnessed a renaissance in the development of DNP, especially at high magnetic fields, and its application in several areas including biophysics, chemistry, structural biology and materials science. Recent technical and theoretical advances have expanded our understanding of established experiments: for example, the cross effect DNP in samples spinning at the magic angle. Furthermore, new experiments suggest that our understanding of the Overhauser effect and its applicability to insulating solids needs to be re-examined. In this article, we summarize important results of the past few years and provide quantum mechanical explanations underlying these results. We also discuss future directions of DNP and current limitations, including the problem of resolution in protein spectra recorded at 80–100 K. National Institute for Biomedical Imaging and Bioengineering (U.S.) (EB-002804) National Institute for Biomedical Imaging and Bioengineering (U.S.) (EB-001960) National Institute for Biomedical Imaging and Bioengineering (U.S.) (EB-003151) National Institute for Biomedical Imaging and Bioengineering (U.S.) (EB-002026) 2017-05-03T19:34:22Z 2017-05-03T19:34:22Z 2015-03 2015-02 Article http://purl.org/eprint/type/JournalArticle 1090-7807 1096-0856 http://hdl.handle.net/1721.1/108646 Can, T.V.; Ni, Q.Z. and Griffin, R.G. “Mechanisms of Dynamic Nuclear Polarization in Insulating Solids.” Journal of Magnetic Resonance 253 (April 2015): 23–35. © 2015 Elsevier Inc https://orcid.org/0000-0001-9092-612X https://orcid.org/0000-0003-1589-832X en_US http://dx.doi.org/10.1016/j.jmr.2015.02.005 Journal of Magnetic Resonance Creative Commons Attribution-NonCommercial-NoDerivs License http://creativecommons.org/licenses/by-nc-nd/4.0/ application/pdf Elsevier PMC |
| spellingShingle | Ni, Qing Zhe Griffin, Robert Guy Can, Thach V Mechanisms of dynamic nuclear polarization in insulating solids |
| title | Mechanisms of dynamic nuclear polarization in insulating solids |
| title_full | Mechanisms of dynamic nuclear polarization in insulating solids |
| title_fullStr | Mechanisms of dynamic nuclear polarization in insulating solids |
| title_full_unstemmed | Mechanisms of dynamic nuclear polarization in insulating solids |
| title_short | Mechanisms of dynamic nuclear polarization in insulating solids |
| title_sort | mechanisms of dynamic nuclear polarization in insulating solids |
| url | http://hdl.handle.net/1721.1/108646 https://orcid.org/0000-0001-9092-612X https://orcid.org/0000-0003-1589-832X |
| work_keys_str_mv | AT niqingzhe mechanismsofdynamicnuclearpolarizationininsulatingsolids AT griffinrobertguy mechanismsofdynamicnuclearpolarizationininsulatingsolids AT canthachv mechanismsofdynamicnuclearpolarizationininsulatingsolids |