Selenoprotein H is an essential regulator of redox homeostasis that cooperates with p53 in development and tumorigenesis

Selenium, an essential micronutrient known for its cancer prevention properties, is incorporated into a class of selenocysteine-containing proteins (selenoproteins). Selenoprotein H (SepH) is a recently identified nucleolar oxidoreductase whose function is not well understood. Here we report that se...

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Bibliographic Details
Main Authors: Cox, Andrew G., Tsomides, Allison, Kim, Andrew J., Saunders, Diane, Hwang, Katie L., Evason, Kimberley J., Heidel, Jerry, Brown, Kristin K., Yuan, Min, Lien, Evan C., Lee, Byung Cheon, Nissim, Sahar, Dickinson, Bryan, Chhangawala, Sagar, Asara, John M., Houvras, Yariv, Gladyshev, Vadim N., Goessling, Wolfram, Chang, Christopher J., 1974-
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Format: Article
Language:en_US
Published: National Academy of Sciences (U.S.) 2017
Online Access:http://hdl.handle.net/1721.1/108671