Selenoprotein H is an essential regulator of redox homeostasis that cooperates with p53 in development and tumorigenesis
Selenium, an essential micronutrient known for its cancer prevention properties, is incorporated into a class of selenocysteine-containing proteins (selenoproteins). Selenoprotein H (SepH) is a recently identified nucleolar oxidoreductase whose function is not well understood. Here we report that se...
Main Authors: | Cox, Andrew G., Tsomides, Allison, Kim, Andrew J., Saunders, Diane, Hwang, Katie L., Evason, Kimberley J., Heidel, Jerry, Brown, Kristin K., Yuan, Min, Lien, Evan C., Lee, Byung Cheon, Nissim, Sahar, Dickinson, Bryan, Chhangawala, Sagar, Asara, John M., Houvras, Yariv, Gladyshev, Vadim N., Goessling, Wolfram, Chang, Christopher J., 1974- |
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Other Authors: | Massachusetts Institute of Technology. Institute for Medical Engineering & Science |
Format: | Article |
Language: | en_US |
Published: |
National Academy of Sciences (U.S.)
2017
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Online Access: | http://hdl.handle.net/1721.1/108671 |
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