Multiple mechanisms contribute to double-strand break repair at rereplication forks in Drosophila follicle cells

Rereplication generates double-strand breaks (DSBs) at sites of fork collisions and causes genomic damage, including repeat instability and chromosomal aberrations. However, the primary mechanism used to repair rereplication DSBs varies across different experimental systems. In Drosophila follicle c...

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Bibliographic Details
Main Authors: Beagan, Kelly, McVey, Mitch, Alexander, Jessica Lynne, Orr-Weaver, Terry
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: National Academy of Sciences (U.S.) 2017
Online Access:http://hdl.handle.net/1721.1/108854
https://orcid.org/0000-0003-4643-2282
https://orcid.org/0000-0002-7934-111X