Google Glass-Directed Monitoring and Control of Microfluidic Biosensors and Actuators
Google Glass is a recently designed wearable device capable of displaying information in a smartphone-like hands-free format by wireless communication. The Glass also provides convenient control over remote devices, primarily enabled by voice recognition commands. These unique features of the Google...
| Main Authors: | , , , , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | en_US |
| Published: |
Nature Publishing Group
2017
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| Online Access: | http://hdl.handle.net/1721.1/109186 |
| _version_ | 1811083478588981248 |
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| author | Carrara, Sandro Demarchi, Danilo Zhang, Yu Shrike Busignani, Fabio Ribas, João Aleman, Julio Rodrigues, Talles Nascimento Shaegh, Seyed Ali Mousavi Massa, Solange Rossi, Camilla Baj Taurino, Irene Shin, Su-Ryon Calzone, Giovanni Amaratunga, Givan Mark Chambers, Douglas L. Jabari, Saman Niu, Yuxi Manoharan, Vijayan Dokmeci, Mehmet R. Khademhosseini, Ali |
| author2 | Massachusetts Institute of Technology. Institute for Medical Engineering & Science |
| author_facet | Massachusetts Institute of Technology. Institute for Medical Engineering & Science Carrara, Sandro Demarchi, Danilo Zhang, Yu Shrike Busignani, Fabio Ribas, João Aleman, Julio Rodrigues, Talles Nascimento Shaegh, Seyed Ali Mousavi Massa, Solange Rossi, Camilla Baj Taurino, Irene Shin, Su-Ryon Calzone, Giovanni Amaratunga, Givan Mark Chambers, Douglas L. Jabari, Saman Niu, Yuxi Manoharan, Vijayan Dokmeci, Mehmet R. Khademhosseini, Ali |
| author_sort | Carrara, Sandro |
| collection | MIT |
| description | Google Glass is a recently designed wearable device capable of displaying information in a smartphone-like hands-free format by wireless communication. The Glass also provides convenient control over remote devices, primarily enabled by voice recognition commands. These unique features of the Google Glass make it useful for medical and biomedical applications where hands-free experiences are strongly preferred. Here, we report for the first time, an integral set of hardware, firmware, software, and Glassware that enabled wireless transmission of sensor data onto the Google Glass for on-demand data visualization and real-time analysis. Additionally, the platform allowed the user to control outputs entered through the Glass, therefore achieving bi-directional Glass-device interfacing. Using this versatile platform, we demonstrated its capability in monitoring physical and physiological parameters such as temperature, pH, and morphology of liver- and heart-on-chips. Furthermore, we showed the capability to remotely introduce pharmaceutical compounds into a microfluidic human primary liver bioreactor at desired time points while monitoring their effects through the Glass. We believe that such an innovative platform, along with its concept, has set up a premise in wearable monitoring and controlling technology for a wide variety of applications in biomedicine. |
| first_indexed | 2024-09-23T12:33:42Z |
| format | Article |
| id | mit-1721.1/109186 |
| institution | Massachusetts Institute of Technology |
| language | en_US |
| last_indexed | 2024-09-23T12:33:42Z |
| publishDate | 2017 |
| publisher | Nature Publishing Group |
| record_format | dspace |
| spelling | mit-1721.1/1091862022-09-28T08:37:20Z Google Glass-Directed Monitoring and Control of Microfluidic Biosensors and Actuators Carrara, Sandro Demarchi, Danilo Zhang, Yu Shrike Busignani, Fabio Ribas, João Aleman, Julio Rodrigues, Talles Nascimento Shaegh, Seyed Ali Mousavi Massa, Solange Rossi, Camilla Baj Taurino, Irene Shin, Su-Ryon Calzone, Giovanni Amaratunga, Givan Mark Chambers, Douglas L. Jabari, Saman Niu, Yuxi Manoharan, Vijayan Dokmeci, Mehmet R. Khademhosseini, Ali Massachusetts Institute of Technology. Institute for Medical Engineering & Science Harvard University--MIT Division of Health Sciences and Technology Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science Khademhosseini, Alireza Zhang, Yu Shrike Busignani, Fabio Ribas, João Aleman, Julio Rodrigues, Talles Nascimento Shaegh, Seyed Ali Mousavi Massa, Solange Rossi, Camilla Baj Taurino, Irene Shin, Su-Ryon Calzone, Giovanni Amaratunga, Givan Mark Chambers, Douglas L. Jabari, Saman Niu, Yuxi Manoharan, Vijayan Dokmeci, Mehmet R. Google Glass is a recently designed wearable device capable of displaying information in a smartphone-like hands-free format by wireless communication. The Glass also provides convenient control over remote devices, primarily enabled by voice recognition commands. These unique features of the Google Glass make it useful for medical and biomedical applications where hands-free experiences are strongly preferred. Here, we report for the first time, an integral set of hardware, firmware, software, and Glassware that enabled wireless transmission of sensor data onto the Google Glass for on-demand data visualization and real-time analysis. Additionally, the platform allowed the user to control outputs entered through the Glass, therefore achieving bi-directional Glass-device interfacing. Using this versatile platform, we demonstrated its capability in monitoring physical and physiological parameters such as temperature, pH, and morphology of liver- and heart-on-chips. Furthermore, we showed the capability to remotely introduce pharmaceutical compounds into a microfluidic human primary liver bioreactor at desired time points while monitoring their effects through the Glass. We believe that such an innovative platform, along with its concept, has set up a premise in wearable monitoring and controlling technology for a wide variety of applications in biomedicine. United States. Defense Threat Reduction Agency (Space and Naval Warfare Systems Center Pacific (SSC PACIFIC) Contract No. N66001-13-C-2027) United States. Office of Naval Research (Young National Investigator Award) National Institutes of Health (U.S.) (EB012597) National Institutes of Health (U.S.) (AR057837) National Institutes of Health (U.S.) (DE021468) National Institutes of Health (U.S.) (HL099073) National Institutes of Health (U.S.) (R56AI105024) United States. Office of Naval Research. Presidential Early Career Award for Scientists and Engineers 2017-05-18T20:58:05Z 2017-05-18T20:58:05Z 2016-03 2015-12 Article http://purl.org/eprint/type/JournalArticle 2045-2322 http://hdl.handle.net/1721.1/109186 Zhang, Yu Shrike et al. “Google Glass-Directed Monitoring and Control of Microfluidic Biosensors and Actuators.” Scientific Reports 6.1 (2016): n. pag. en_US http://dx.doi.org/10.1038/srep22237 Scientific Reports Creative Commons Attribution http://creativecommons.org/licenses/by/4.0/ application/pdf Nature Publishing Group Nature Publishing Group |
| spellingShingle | Carrara, Sandro Demarchi, Danilo Zhang, Yu Shrike Busignani, Fabio Ribas, João Aleman, Julio Rodrigues, Talles Nascimento Shaegh, Seyed Ali Mousavi Massa, Solange Rossi, Camilla Baj Taurino, Irene Shin, Su-Ryon Calzone, Giovanni Amaratunga, Givan Mark Chambers, Douglas L. Jabari, Saman Niu, Yuxi Manoharan, Vijayan Dokmeci, Mehmet R. Khademhosseini, Ali Google Glass-Directed Monitoring and Control of Microfluidic Biosensors and Actuators |
| title | Google Glass-Directed Monitoring and Control of Microfluidic Biosensors and Actuators |
| title_full | Google Glass-Directed Monitoring and Control of Microfluidic Biosensors and Actuators |
| title_fullStr | Google Glass-Directed Monitoring and Control of Microfluidic Biosensors and Actuators |
| title_full_unstemmed | Google Glass-Directed Monitoring and Control of Microfluidic Biosensors and Actuators |
| title_short | Google Glass-Directed Monitoring and Control of Microfluidic Biosensors and Actuators |
| title_sort | google glass directed monitoring and control of microfluidic biosensors and actuators |
| url | http://hdl.handle.net/1721.1/109186 |
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