Molecular Basis for Self-Assembly of a Human Host-Defense Peptide That Entraps Bacterial Pathogens
Human α-defensin 6 (HD6) is a 32-aa cysteine-rich peptide of the innate immune system. Although HD6 is a member of an antimicrobial peptide family, it exhibits negligible antibacterial activity in vitro. Rather, HD6 possesses a unique innate immune mechanism whereby it self-assembles into oligomers...
| Main Authors: | , |
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| Format: | Article |
| Language: | en_US |
| Published: |
American Chemical Society (ACS)
2017
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| Online Access: | http://hdl.handle.net/1721.1/109287 https://orcid.org/0000-0002-5356-3638 https://orcid.org/0000-0002-6153-8803 |