Peanut oral immunotherapy transiently expands circulating Ara h 2–specific B cells with a homologous repertoire in unrelated subjects
Background Peanut oral immunotherapy (PNOIT) induces persistent tolerance to peanut in a subset of patients and induces specific antibodies that might play a role in clinical protection. However, the contribution of induced antibody clones to clinical tolerance in PNOIT is unknown. Objective...
Main Authors: | Calatroni, Agustin, Tadigotla, Vasisht R., Ruiter, Bert, Ma, Alex, Moon, James, Shreffler, Wayne G., Patil, Sarita, Ogunniyi, Adebola Oluwakayode, Love, John C |
---|---|
Other Authors: | Massachusetts Institute of Technology. Department of Chemical Engineering |
Format: | Article |
Language: | en_US |
Published: |
Elsevier
2017
|
Online Access: | http://hdl.handle.net/1721.1/109437 https://orcid.org/0000-0002-2172-2286 https://orcid.org/0000-0003-0921-3144 |
Similar Items
-
Expansion of the CD4+ effector T-cell repertoire characterizes peanut-allergic patients with heightened clinical sensitivity
by: Ruiter, Bert, et al.
Published: (2021) -
Single-Cell Analysis Reveals Isotype-Specific Autoreactive B Cell Repertoires in Sjögren’s Syndrome
by: Nguyen, Cuong Q., et al.
Published: (2013) -
Single-cell analysis reveals isotype-specific autoreactive B cell repertoires in Sjögren's syndrome.
by: Cuong Q Nguyen, et al.
Published: (2013-01-01) -
Peanut oral immunotherapy differentially suppresses clonally distinct subsets of T helper cells
by: Brinda Monian, et al.
Published: (2022-01-01) -
Boiling and Frying Peanuts Decreases Soluble Peanut (Arachis Hypogaea) Allergens Ara h 1 and Ara h 2 But Does Not Generate Hypoallergenic Peanuts.
by: Sarah S Comstock, et al.
Published: (2016-01-01)