Automated pipeline for rapid production and screening of HIV-specific monoclonal antibodies using pichia pastoris
Monoclonal antibodies (mAbs) that bind and neutralize human pathogens have great therapeutic potential. Advances in automated screening and liquid handling have resulted in the ability to discover antigen-specific antibodies either directly from human blood or from various combinatorial libraries (...
Main Authors: | Shah, Kartik A, Clark, John J, Goods, Brittany A., Politano, Timothy James, Mozdzierz, Nicholas Joseph, Zimnisky, Ross, Leeson, Rachel, Love, John C, Love, Kerry R. |
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Other Authors: | Massachusetts Institute of Technology. Center for Biomedical Innovation |
Format: | Article |
Language: | en_US |
Published: |
Wiley Blackwell
2017
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Online Access: | http://hdl.handle.net/1721.1/109438 https://orcid.org/0000-0003-0921-3144 |
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