Proteomic Mapping of the Human Mitochondrial Intermembrane Space in Live Cells via Ratiometric APEX Tagging
Obtaining complete protein inventories for subcellular regions is a challenge that often limits our understanding of cellular function, especially for regions that are impossible to purify and are therefore inaccessible to traditional proteomic analysis. We recently developed a method to map proteom...
Main Authors: | Udeshi, Namrata D., Cracan, Valentin, Svinkina, Tanya, Hung, Victoria, Zou, Peng, Rhee, Hyun-Woo, Carr, Steven A, Mootha, Vamsi, Ting, Alice Y |
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Other Authors: | Broad Institute of MIT and Harvard |
Format: | Article |
Language: | en_US |
Published: |
Elsevier
2017
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Online Access: | http://hdl.handle.net/1721.1/109554 https://orcid.org/0000-0003-3972-2820 https://orcid.org/0000-0001-5319-3860 https://orcid.org/0000-0002-7203-4299 https://orcid.org/0000-0002-8277-5226 |
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