Monitoring global protein thiol-oxidation and protein S-mycothiolation in Mycobacterium smegmatis under hypochlorite stress

Monitoring global protein thiol-oxidation and protein S-mycothiolation in Mycobacterium smegmatis under hypochlorite stress

Mycothiol (MSH) is the major low molecular weight (LMW) thiol in Actinomycetes. Here, we used shotgun proteomics, OxICAT and RNA-seq transcriptomics to analyse protein S-mycothiolation, reversible thiol-oxidations and their impact on gene expression in Mycobacterium smegmatis under hypochlorite stre...

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Bibliographic Details
Main Authors: Hillion, Melanie, Busche, Tobias, Rossius, Martina, Rawat, Mamta, Wirtz, Markus, Antelmann, Haike, Bernhardt, Jorg, Maas, Sandra, Becher, Dorte, Hell, Ruediger, Kalinowski, Jorn, Rueckert, Christian
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Nature Publishing Group 2017
Online Access:http://hdl.handle.net/1721.1/110027

Internet

http://hdl.handle.net/1721.1/110027

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