Monitoring global protein thiol-oxidation and protein S-mycothiolation in Mycobacterium smegmatis under hypochlorite stress
Mycothiol (MSH) is the major low molecular weight (LMW) thiol in Actinomycetes. Here, we used shotgun proteomics, OxICAT and RNA-seq transcriptomics to analyse protein S-mycothiolation, reversible thiol-oxidations and their impact on gene expression in Mycobacterium smegmatis under hypochlorite stre...
Main Authors: | Hillion, Melanie, Busche, Tobias, Rossius, Martina, Rawat, Mamta, Wirtz, Markus, Antelmann, Haike, Bernhardt, Jorg, Maas, Sandra, Becher, Dorte, Hell, Ruediger, Kalinowski, Jorn, Rueckert, Christian |
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Other Authors: | Massachusetts Institute of Technology. Department of Biology |
Format: | Article |
Language: | en_US |
Published: |
Nature Publishing Group
2017
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Online Access: | http://hdl.handle.net/1721.1/110027 |
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