Hyper- and hypo- nutrition studies of the hepatic transcriptome and epigenome suggest that PPARα regulates anaerobic glycolysis

Hyper- and hypo- nutrition studies of the hepatic transcriptome and epigenome suggest that PPARα regulates anaerobic glycolysis

Diet plays a crucial role in shaping human health and disease. Diets promoting obesity and insulin resistance can lead to severe metabolic diseases, while calorie-restricted (CR) diets can improve health and extend lifespan. In this work, we fed mice either a chow diet (CD), a 16 week high-fat diet...

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Bibliographic Details
Main Authors: Vernia, Santiago, Kennedy, Norman J., Davis, Roger J., Soltis, Anthony Robert, Motola, Shmulik, Ng, Christopher W., Dalin, Simona, Matthews, Bryan, Fraenkel, Ernest
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: Nature Publishing Group 2017
Online Access:http://hdl.handle.net/1721.1/110055
https://orcid.org/0000-0003-1381-4313
https://orcid.org/0000-0001-5024-9718
https://orcid.org/0000-0001-9249-8181

Internet

http://hdl.handle.net/1721.1/110055
https://orcid.org/0000-0003-1381-4313
https://orcid.org/0000-0001-5024-9718
https://orcid.org/0000-0001-9249-8181

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