Deployable micro-traps to sequester motile bacteria
The development of strategies to reduce the load of unwanted bacteria is a fundamental challenge in industrial processing, environmental sciences and medical applications. Here, we report a new method to sequester motile bacteria from a liquid, based on passive, deployable micro-traps that confine b...
| Main Authors: | , , , , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | en_US |
| Published: |
Nature Publishing Group
2017
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| Online Access: | http://hdl.handle.net/1721.1/110072 https://orcid.org/0000-0002-3199-0508 |
| _version_ | 1811072136435990528 |
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| author | Di Giacomo, Raffaele Krödel, Sebastian Maresca, Bruno Benzoni, Patrizia Daraio, Chiara Rusconi, Roberto Stocker, Roman |
| author2 | Massachusetts Institute of Technology. Department of Civil and Environmental Engineering |
| author_facet | Massachusetts Institute of Technology. Department of Civil and Environmental Engineering Di Giacomo, Raffaele Krödel, Sebastian Maresca, Bruno Benzoni, Patrizia Daraio, Chiara Rusconi, Roberto Stocker, Roman |
| author_sort | Di Giacomo, Raffaele |
| collection | MIT |
| description | The development of strategies to reduce the load of unwanted bacteria is a fundamental challenge in industrial processing, environmental sciences and medical applications. Here, we report a new method to sequester motile bacteria from a liquid, based on passive, deployable micro-traps that confine bacteria using micro-funnels that open into trapping chambers. Even in low concentrations, micro-traps afford a 70% reduction in the amount of bacteria in a liquid sample, with a potential to reach >90% as shown by modelling improved geometries. This work introduces a new approach to contain the growth of bacteria without chemical means, an advantage of particular importance given the alarming growth of pan-drug-resistant bacteria. |
| first_indexed | 2024-09-23T09:01:28Z |
| format | Article |
| id | mit-1721.1/110072 |
| institution | Massachusetts Institute of Technology |
| language | en_US |
| last_indexed | 2024-09-23T09:01:28Z |
| publishDate | 2017 |
| publisher | Nature Publishing Group |
| record_format | dspace |
| spelling | mit-1721.1/1100722022-09-26T09:56:20Z Deployable micro-traps to sequester motile bacteria Di Giacomo, Raffaele Krödel, Sebastian Maresca, Bruno Benzoni, Patrizia Daraio, Chiara Rusconi, Roberto Stocker, Roman Massachusetts Institute of Technology. Department of Civil and Environmental Engineering Massachusetts Institute of Technology. Department of Nuclear Science and Engineering Rusconi, Roberto Stocker, Roman The development of strategies to reduce the load of unwanted bacteria is a fundamental challenge in industrial processing, environmental sciences and medical applications. Here, we report a new method to sequester motile bacteria from a liquid, based on passive, deployable micro-traps that confine bacteria using micro-funnels that open into trapping chambers. Even in low concentrations, micro-traps afford a 70% reduction in the amount of bacteria in a liquid sample, with a potential to reach >90% as shown by modelling improved geometries. This work introduces a new approach to contain the growth of bacteria without chemical means, an advantage of particular importance given the alarming growth of pan-drug-resistant bacteria. Swiss National Science Foundation (Grant "MechNanoTruss-Mechanical response of polymer nanotruss scaffolds“(Grant No. 164375)) 2017-06-20T18:00:20Z 2017-06-20T18:00:20Z 2017-04 2016-10 Article http://purl.org/eprint/type/JournalArticle 2045-2322 http://hdl.handle.net/1721.1/110072 Di Giacomo, Raffaele, Sebastian Krödel, Bruno Maresca, Patrizia Benzoni, Roberto Rusconi, Roman Stocker, and Chiara Daraio. “Deployable Micro-Traps to Sequester Motile Bacteria.” Scientific Reports 7 (April 5, 2017): 45897. https://orcid.org/0000-0002-3199-0508 en_US http://dx.doi.org/10.1038/srep45897 Scientific Reports Creative Commons Attribution 4.0 International License http://creativecommons.org/licenses/by/4.0/ application/pdf Nature Publishing Group Nature |
| spellingShingle | Di Giacomo, Raffaele Krödel, Sebastian Maresca, Bruno Benzoni, Patrizia Daraio, Chiara Rusconi, Roberto Stocker, Roman Deployable micro-traps to sequester motile bacteria |
| title | Deployable micro-traps to sequester motile bacteria |
| title_full | Deployable micro-traps to sequester motile bacteria |
| title_fullStr | Deployable micro-traps to sequester motile bacteria |
| title_full_unstemmed | Deployable micro-traps to sequester motile bacteria |
| title_short | Deployable micro-traps to sequester motile bacteria |
| title_sort | deployable micro traps to sequester motile bacteria |
| url | http://hdl.handle.net/1721.1/110072 https://orcid.org/0000-0002-3199-0508 |
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