Organization of high-level visual cortex in human infants
How much of the structure of the human mind and brain is already specified at birth, and how much arises from experience? In this article, we consider the test case of extrastriate visual cortex, where a highly systematic functional organization is present in virtually every normal adult, including...
| Main Authors: | , , , , , , , |
|---|---|
| Other Authors: | |
| Format: | Article |
| Language: | en_US |
| Published: |
Nature Publishing Group
2017
|
| Online Access: | http://hdl.handle.net/1721.1/110074 https://orcid.org/0000-0002-3812-4258 https://orcid.org/0000-0003-3444-805X https://orcid.org/0000-0003-3853-7885 https://orcid.org/0000-0003-2377-1791 |
| _version_ | 1811086016556040192 |
|---|---|
| author | Keil, Boris Deen, Benjamin Matthew Richardson, Hilary Dilks, Daniel D Takahashi, Atsushi Wald, Lawrence Kanwisher, Nancy Saxe, Rebecca R |
| author2 | Harvard University--MIT Division of Health Sciences and Technology |
| author_facet | Harvard University--MIT Division of Health Sciences and Technology Keil, Boris Deen, Benjamin Matthew Richardson, Hilary Dilks, Daniel D Takahashi, Atsushi Wald, Lawrence Kanwisher, Nancy Saxe, Rebecca R |
| author_sort | Keil, Boris |
| collection | MIT |
| description | How much of the structure of the human mind and brain is already specified at birth, and how much arises from experience? In this article, we consider the test case of extrastriate visual cortex, where a highly systematic functional organization is present in virtually every normal adult, including regions preferring behaviourally significant stimulus categories, such as faces, bodies, and scenes. Novel methods were developed to scan awake infants with fMRI, while they viewed multiple categories of visual stimuli. Here we report that the visual cortex of 4–6-month-old infants contains regions that respond preferentially to abstract categories (faces and scenes), with a spatial organization similar to adults. However, precise response profiles and patterns of activity across multiple visual categories differ between infants and adults. These results demonstrate that the large-scale organization of category preferences in visual cortex is adult-like within a few months after birth, but is subsequently refined through development. |
| first_indexed | 2024-09-23T13:19:34Z |
| format | Article |
| id | mit-1721.1/110074 |
| institution | Massachusetts Institute of Technology |
| language | en_US |
| last_indexed | 2024-09-23T13:19:34Z |
| publishDate | 2017 |
| publisher | Nature Publishing Group |
| record_format | dspace |
| spelling | mit-1721.1/1100742022-10-01T14:32:17Z Organization of high-level visual cortex in human infants Keil, Boris Deen, Benjamin Matthew Richardson, Hilary Dilks, Daniel D Takahashi, Atsushi Wald, Lawrence Kanwisher, Nancy Saxe, Rebecca R Harvard University--MIT Division of Health Sciences and Technology Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences McGovern Institute for Brain Research at MIT Deen, Benjamin Matthew Richardson, Hilary Dilks, Daniel D Takahashi, Atsushi Wald, Lawrence Kanwisher, Nancy Saxe, Rebecca R How much of the structure of the human mind and brain is already specified at birth, and how much arises from experience? In this article, we consider the test case of extrastriate visual cortex, where a highly systematic functional organization is present in virtually every normal adult, including regions preferring behaviourally significant stimulus categories, such as faces, bodies, and scenes. Novel methods were developed to scan awake infants with fMRI, while they viewed multiple categories of visual stimuli. Here we report that the visual cortex of 4–6-month-old infants contains regions that respond preferentially to abstract categories (faces and scenes), with a spatial organization similar to adults. However, precise response profiles and patterns of activity across multiple visual categories differ between infants and adults. These results demonstrate that the large-scale organization of category preferences in visual cortex is adult-like within a few months after birth, but is subsequently refined through development. National Science Foundation (U.S.) (CCF-1231216) 2017-06-20T18:03:54Z 2017-06-20T18:03:54Z 2017-01 2016-08 Article http://purl.org/eprint/type/JournalArticle 2041-1723 http://hdl.handle.net/1721.1/110074 Deen, Ben; Richardson, Hilary; Dilks, Daniel D.; Takahashi, Atsushi; Keil, Boris; Wald, Lawrence L.; Kanwisher, Nancy and Saxe, Rebecca “Organization of High-Level Visual Cortex in Human Infants.” Nature Communications 8 (January 2017): 13995 © 2017 The Author(s) https://orcid.org/0000-0002-3812-4258 https://orcid.org/0000-0003-3444-805X https://orcid.org/0000-0003-3853-7885 https://orcid.org/0000-0003-2377-1791 en_US http://dx.doi.org/10.1038/ncomms13995 Nature Communications Creative Commons Attribution 4.0 International License http://creativecommons.org/licenses/by/4.0/ application/pdf Nature Publishing Group Nature |
| spellingShingle | Keil, Boris Deen, Benjamin Matthew Richardson, Hilary Dilks, Daniel D Takahashi, Atsushi Wald, Lawrence Kanwisher, Nancy Saxe, Rebecca R Organization of high-level visual cortex in human infants |
| title | Organization of high-level visual cortex in human infants |
| title_full | Organization of high-level visual cortex in human infants |
| title_fullStr | Organization of high-level visual cortex in human infants |
| title_full_unstemmed | Organization of high-level visual cortex in human infants |
| title_short | Organization of high-level visual cortex in human infants |
| title_sort | organization of high level visual cortex in human infants |
| url | http://hdl.handle.net/1721.1/110074 https://orcid.org/0000-0002-3812-4258 https://orcid.org/0000-0003-3444-805X https://orcid.org/0000-0003-3853-7885 https://orcid.org/0000-0003-2377-1791 |
| work_keys_str_mv | AT keilboris organizationofhighlevelvisualcortexinhumaninfants AT deenbenjaminmatthew organizationofhighlevelvisualcortexinhumaninfants AT richardsonhilary organizationofhighlevelvisualcortexinhumaninfants AT dilksdanield organizationofhighlevelvisualcortexinhumaninfants AT takahashiatsushi organizationofhighlevelvisualcortexinhumaninfants AT waldlawrence organizationofhighlevelvisualcortexinhumaninfants AT kanwishernancy organizationofhighlevelvisualcortexinhumaninfants AT saxerebeccar organizationofhighlevelvisualcortexinhumaninfants |