A Novel Point-of-Care Smartphone Based System for Monitoring the Cardiac and Respiratory Systems
Cardio-respiratory monitoring is one of the most demanding areas in the rapidly growing, mobile-device, based health care delivery. We developed a 12-lead smartphone-based electrocardiogram (ECG) acquisition and monitoring system (called “cvrPhone”), and an application to assess underlying ischemia,...
| Main Authors: | , , , , , , , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | en_US |
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Nature Publishing Group
2017
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| Online Access: | http://hdl.handle.net/1721.1/110077 |
| _version_ | 1826189649319559168 |
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| author | Sohn, Kwanghyun Merchant, Faisal M. Sayadi, Omid Puppala, Dheeraj Doddamani, Rajiv Sahani, Ashish Singh, Jagmeet P. Heist, E. Kevin Isselbacher, Eric M. Armoundas, Antonis |
| author2 | Massachusetts Institute of Technology. Institute for Medical Engineering & Science |
| author_facet | Massachusetts Institute of Technology. Institute for Medical Engineering & Science Sohn, Kwanghyun Merchant, Faisal M. Sayadi, Omid Puppala, Dheeraj Doddamani, Rajiv Sahani, Ashish Singh, Jagmeet P. Heist, E. Kevin Isselbacher, Eric M. Armoundas, Antonis |
| author_sort | Sohn, Kwanghyun |
| collection | MIT |
| description | Cardio-respiratory monitoring is one of the most demanding areas in the rapidly growing, mobile-device, based health care delivery. We developed a 12-lead smartphone-based electrocardiogram (ECG) acquisition and monitoring system (called “cvrPhone”), and an application to assess underlying ischemia, and estimate the respiration rate (RR) and tidal volume (TV) from analysis of electrocardiographic (ECG) signals only. During in-vivo swine studies (n = 6), 12-lead ECG signals were recorded at baseline and following coronary artery occlusion. Ischemic indices calculated from each lead showed statistically significant (p < 0.05) increase within 2 min of occlusion compared to baseline. Following myocardial infarction, spontaneous ventricular tachycardia episodes (n = 3) were preceded by significant (p < 0.05) increase of the ischemic index ~1–4 min prior to the onset of the tachy-arrhythmias. In order to assess the respiratory status during apnea, the mechanical ventilator was paused for up to 2 min during normal breathing. We observed that the RR and TV estimation algorithms detected apnea within 7.9 ± 1.1 sec and 5.5 ± 2.2 sec, respectively, while the estimated RR and TV values were 0 breaths/min and less than 100 ml, respectively. In conclusion, the cvrPhone can be used to detect myocardial ischemia and periods of respiratory apnea using a readily available mobile platform. |
| first_indexed | 2024-09-23T08:18:57Z |
| format | Article |
| id | mit-1721.1/110077 |
| institution | Massachusetts Institute of Technology |
| language | en_US |
| last_indexed | 2024-09-23T08:18:57Z |
| publishDate | 2017 |
| publisher | Nature Publishing Group |
| record_format | dspace |
| spelling | mit-1721.1/1100772024-03-20T19:35:01Z A Novel Point-of-Care Smartphone Based System for Monitoring the Cardiac and Respiratory Systems Sohn, Kwanghyun Merchant, Faisal M. Sayadi, Omid Puppala, Dheeraj Doddamani, Rajiv Sahani, Ashish Singh, Jagmeet P. Heist, E. Kevin Isselbacher, Eric M. Armoundas, Antonis Massachusetts Institute of Technology. Institute for Medical Engineering & Science Armoundas, Antonis Cardio-respiratory monitoring is one of the most demanding areas in the rapidly growing, mobile-device, based health care delivery. We developed a 12-lead smartphone-based electrocardiogram (ECG) acquisition and monitoring system (called “cvrPhone”), and an application to assess underlying ischemia, and estimate the respiration rate (RR) and tidal volume (TV) from analysis of electrocardiographic (ECG) signals only. During in-vivo swine studies (n = 6), 12-lead ECG signals were recorded at baseline and following coronary artery occlusion. Ischemic indices calculated from each lead showed statistically significant (p < 0.05) increase within 2 min of occlusion compared to baseline. Following myocardial infarction, spontaneous ventricular tachycardia episodes (n = 3) were preceded by significant (p < 0.05) increase of the ischemic index ~1–4 min prior to the onset of the tachy-arrhythmias. In order to assess the respiratory status during apnea, the mechanical ventilator was paused for up to 2 min during normal breathing. We observed that the RR and TV estimation algorithms detected apnea within 7.9 ± 1.1 sec and 5.5 ± 2.2 sec, respectively, while the estimated RR and TV values were 0 breaths/min and less than 100 ml, respectively. In conclusion, the cvrPhone can be used to detect myocardial ischemia and periods of respiratory apnea using a readily available mobile platform. American Heart Association (15GRNT23070001) United States. National Institutes of Health (1 R01 HL135335–01) American Heart Association (15POST22690003) United States. National Institutes of Health (8UL1TR000170-05) 2017-06-20T18:30:08Z 2017-06-20T18:30:08Z 2017-03 2016-11 Article http://purl.org/eprint/type/JournalArticle 2045-2322 http://hdl.handle.net/1721.1/110077 Sohn, Kwanghyun; Merchant, Faisal M.; Sayadi, Omid; Puppala, Dheeraj; Doddamani, Rajiv; Sahani, Ashish; Singh, Jagmeet P.; Heist, E. Kevin; Isselbacher, Eric M. and Armoundas, Antonis A. “A Novel Point-of-Care Smartphone Based System for Monitoring the Cardiac and Respiratory Systems.” Scientific Reports 7 (March 2017): 44946 © 2017 The Author(s) en_US http://dx.doi.org/10.1038/srep44946 Scientific Reports Creative Commons Attribution 4.0 International License http://creativecommons.org/licenses/by/4.0/ application/pdf Nature Publishing Group Nature |
| spellingShingle | Sohn, Kwanghyun Merchant, Faisal M. Sayadi, Omid Puppala, Dheeraj Doddamani, Rajiv Sahani, Ashish Singh, Jagmeet P. Heist, E. Kevin Isselbacher, Eric M. Armoundas, Antonis A Novel Point-of-Care Smartphone Based System for Monitoring the Cardiac and Respiratory Systems |
| title | A Novel Point-of-Care Smartphone Based System for Monitoring the Cardiac and Respiratory Systems |
| title_full | A Novel Point-of-Care Smartphone Based System for Monitoring the Cardiac and Respiratory Systems |
| title_fullStr | A Novel Point-of-Care Smartphone Based System for Monitoring the Cardiac and Respiratory Systems |
| title_full_unstemmed | A Novel Point-of-Care Smartphone Based System for Monitoring the Cardiac and Respiratory Systems |
| title_short | A Novel Point-of-Care Smartphone Based System for Monitoring the Cardiac and Respiratory Systems |
| title_sort | novel point of care smartphone based system for monitoring the cardiac and respiratory systems |
| url | http://hdl.handle.net/1721.1/110077 |
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