The CENP-L-N Complex Forms a Critical Node in an Integrated Meshwork of Interactions at the Centromere-Kinetochore Interface
During mitosis, the macromolecular kinetochore complex assembles on the centromere to orchestrate chromosome segregation. The properties and architecture of the 16-subunit Constitutive Centromere-Associated Network (CCAN) that allow it to build a robust platform for kinetochore assembly are poorly u...
Main Authors: | Sekulic, Nikolina, Guo, Lucie Y., Black, Ben E., McKinley, Kara Lavidge, Tsinman, Tonia, Cheeseman, Iain M |
---|---|
Other Authors: | Massachusetts Institute of Technology. Department of Biological Engineering |
Format: | Article |
Language: | en_US |
Published: |
Elsevier
2017
|
Online Access: | http://hdl.handle.net/1721.1/110167 https://orcid.org/0000-0001-6283-9168 https://orcid.org/0000-0002-3829-5612 |
Similar Items
-
Polo-like Kinase 1 Licenses CENP-A Deposition at Centromeres
by: McKinley, Kara Lavidge, et al.
Published: (2017) -
Centromeres are maintained by fastening CENP-A to DNA and directing an arginine anchor-dependent nucleosome transition
by: Guo, Lucie Y., et al.
Published: (2018) -
Mechanisms for the propagation and recognition of human centromeres
by: McKinley, Kara Lavidge
Published: (2016) -
Distinct Organization and Regulation of the Outer Kinetochore KMN Network Downstream of CENP-C and CENP-T
by: Rago, Florencia, et al.
Published: (2017) -
Dynamic cell cycle–dependent phosphorylation modulates CENP-L–CENP-N centromere recruitment
by: Navarro, Alexandra P, et al.
Published: (2022)