Microbial interactions and community assembly at microscales

In most environments, microbial interactions take place within microscale cell aggregates. At the scale of these aggregates (∼100 μm), interactions are likely to be the dominant driver of population structure and dynamics. In particular, organisms that exploit interspecific interactions to increase...

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Bibliographic Details
Main Authors: Cordero Sanchez, Otto X., Datta, Manoshi Sen
Other Authors: Massachusetts Institute of Technology. Computational and Systems Biology Program
Format: Article
Language:en_US
Published: Elsevier 2017
Online Access:http://hdl.handle.net/1721.1/110255
https://orcid.org/0000-0001-6843-9843
Description
Summary:In most environments, microbial interactions take place within microscale cell aggregates. At the scale of these aggregates (∼100 μm), interactions are likely to be the dominant driver of population structure and dynamics. In particular, organisms that exploit interspecific interactions to increase ecological performance often co-aggregate. Conversely, organisms that antagonize each other will tend to spatially segregate, creating distinct micro-communities and increased diversity at larger length scales. We argue that, in order to understand the role that biological interactions play in microbial community function, it is necessary to study microscale spatial organization with enough throughput to measure statistical associations between taxa and possible alternative community states. We conclude by proposing strategies to tackle this challenge.